Melo / Goldman Myeloproliferative Disorders

1. Auflage 2007
ISBN: 978-3-540-34506-0
Verlag: Springer Berlin Heidelberg
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 354 Seiten

Reihe: Hematologic Malignancies

This book contains a series of contributions from internationally renowned academics with special expertise in one or other diseases which collectively are grouped under the heading myeloproliferative disorders. For the editors this term includes Ph-positive chronic myeloid leukemia but also the various Ph-negative variants, some of which provide fascinating insights into the molecular mechanisms of leukemia. There have been many recent developments in understanding the Pathophysiology and a number of therapeutic innovations in this area. One particular merit of this book is the speed with which it has been produced – an important factor in this very rapidly moving field.

Autoren/Hrsg.

Melo, J. V.

Goldman, J.

Inhaltsverzeichnis

1;Preface;5
2;Table of Contents;7
3;Contributors;8
4;Chronic Myeloid Leukemia – A Brief History;11
5;Bcr-Abl and Signal Transduction;24
6;Chronic Myeloid Leukemia: Biology of Advanced Phase;45
7;Clinical Features of CML;67
8;Signal Transduction Inhibitors in Chronic Myeloid Leukemia;83
9;Treatment with Tyrosine Kinase Inhibitors;111
10;Allogeneic Transplantation for CML;122
11;Autografting in Chronic Myeloid Leukemia;139
12;Monitoring Disease Response;148
13;New Therapies for Chronic Myeloid Leukemia;170
14;Immune Therapy of Chronic Myelogenous Leukemia;190
15;Therapeutic Strategies and Concepts of Cure in CML;206
16;BCR-ABL-Negative Chronic Myeloid Leukemia;224
17;Hypereosinophilic Syndrome;239
18;Chronic Idiopathic Myelofibrosis;256
19;Polycythemia Vera – Clinical Aspects;280
20;Polycythemia Vera and Other Polycythemic Disorders – Biological Aspects;300
21;Essential Thrombocythemia;323
22;Subject Index;351