Buch, Englisch, 199 Seiten, HC runder Rücken kaschiert, Format (B × H): 160 mm x 241 mm, Gewicht: 4616 g
Reihe: Milestones in Drug Therapy
Pioneering Medicine in Breast Cancer
Buch, Englisch, 199 Seiten, HC runder Rücken kaschiert, Format (B × H): 160 mm x 241 mm, Gewicht: 4616 g
Reihe: Milestones in Drug Therapy
ISBN: 978-3-0348-0663-3
Verlag: Springer
This monograph, written by V. Craig Jordan - known as the “father of tamoxifen” - and his Tamoxifen Team at the Georgetown University Washington DC, illustrates the journey of this milestone in medicine. It includes a personal interview with V. Craig Jordan about his four decades of discovery in breast cancer research and treatment. V. Craig Jordan was there for the birth of tamoxifen as he is credited for reinventing a “failed morning after contraceptive” to become the “gold standard” for the treatment of breast cancer. He contributed to every aspect of tamoxifen application in therapeutics and all aspects of tamoxifen’s pharmacology. He discovered the selective estrogen receptor modulators (SERMs) and explored the new biology of estrogen-induced apoptosis.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
Discovery and Pharmacology of Nonsteroidal Estrogens and Antiestrogens.- Tamoxifen Goes Forward Alone.- Metabolites of Tamoxifen as the Basis of Drug Development.- Adjuvant Therapy – The Breakthrough.- The Wisconsin Story in the 1980’s: Discovery of Target Site Specific Estrogen Action.- Carcinogenesis and Tamoxifen.- Chemoprevention: Cinderella waiting for the ball.- Tamoxifen and Raloxifene head to head: The STAR TRIAL.- Acquired resistance to Tamoxifen: back to the beginning.- The legacy of Tamoxifen.- Appendix: Four decades of discovery in breast cancer research and treatment – an interview with V. Craig Jordan by Marc Poirot.- Selected Awards that Recognize the Contribution of Tamoxifen and Raloxifene to Medicine.
