Maurer / Riederer / Beckmann Alzheimer’s Disease. Epidemiology, Neuropathology, Neurochemistry, and Clinics

Erscheinungsjahr 2013
ISBN: 978-3-7091-3396-5
Verlag: Springer Wien
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 585 Seiten, eBook

Reihe: Key Topics in Brain Research

Zielgruppe

Research

Autoren/Hrsg.

Maurer, Konrad

Riederer, Peter

Beckmann, Helmut

Inhaltsverzeichnis

Some philosophical aspects of Alzheimer’s discovery: an American perspective.- The aging brain and its disorders.- Epidemiology of Alzheimer’s disease.- Descriptive and analytic epidemiology of Alzheimer’s disease.- A proposed classification of familial Alzheimer’s disease based on analysis of 32 multigeneration pedigrees.- Morphology of Alzheimer’s disease and related disorders.- Morphology of white matter, subcortical, dementia in Alzheimer’s disease.- Morphology of the cerebral cortex in relation to Alzheimer’s dementia.- Quantitative investigations of presenile and senile changes of the human entorhinal region.- Neuronal plasticity of the septo-hippocampal pathway in patients suffering from dementia of Alzheimer type.- Morphology of neurofibrillary tangles and senile plaques.- An in vitro model for the study of the neurofibrillary degeneration of the Alzheimer type.- Molecular and cellular changes associated with neurofibrillary tangles and senile plaques.- Brain abnormalities in aged monkeys: a model sharing features with Alzheimer’s disease.- Aged dogs: an animal model to study beta-protein amyloidogenesis.- Immunocytochemical and ultrastructural pathology of nerve cells in Alzheimer’s disease and related disorders.- Choline-acetyltransferase immunoreactivity in the hippocampal formation of control subjects and patients with Alzheimer’s disease.- Calbindin immunoreactive _eurons in Alzheimer-type dementia.- Lactate production and glycolytic enzymes in sporadic and familial Alzheimer’s disease.- Impairment of cerebral glucose metabolism parallels learning and memory dysfunctions after intracerebral streptozotocin.- Choline levels, the regulation of acetylcholine and phosphatidylcholine synthesis, and Alzheimer’s disease.- Acetylcholinesynthesis and membrane phospholipids.- Hippocampal and cardiovascular effects of muscarinic agents.- Cholinergie and monoaminergic neuromediator systems in DAT. Neuropathological and neurochemical findings.- Alterations in catecholamine neurons in the locus coeruleus in dementias of Alzheimer’s and Parkinson’s disease.- Tyrosine hydroxylase, tryptophan hydroxylase, biopterin and neopterin in the brains and biopterin and neopterin in sera from patients with Alzheimer’s disease.- Postreceptorial enhancement of neurotransmission for the treatment of cognitive disorders.- Excitatory dicarboxylic amino acid and pyramidal neurone neurotransmission of the cerebral cortex in Alzheimer’s disease.- The sequence within the two polyadenylation sites of the A4 amyloid peptide precursor stimulates the translation.- Alzheimer-like changes of cortical amino acid transmitters in elderly Down’s syndrome.- Characteristics of learning deficit induced by ibotenic acid lesion of the frontal cortex in rats.- Memory loss by glutamate antagonists: an animal model of Alzheimer’s disease?.- Convulsant properties of methylxanthines, potential cognitive enhancers in dementia syndromes.- Neurodegenerative diseases: CSF amines, lactate and clinical findings.- Somatostatin-like immunoreactivity and neurotransmitter metabolites in the cerebrospinal fluid of patients with senile dementia of Alzheimer type and Parkinson’s disease.- Nerve growth factor in serum of patients with dementia (Alzheimer type).- Neuroendocrine dysfunction in early-onset Alzheimer’s disease.- Urinary excretion of salsolinol enantiomers and 1,2-dehydrosalsolinol in patients with degenerative dementia.- Alzheimer’s disease — one, two or several?.- Diagnostic criteria of Alzheimer’s disease.- Clinicaldiagnosis of Alzheimer’s disease: DSM-III-R, ICD-10 — what else?.- Clinical aspects and terminology of dementing syndromes.- Symptoms of depression in the course of multi-infarct dementia and dementia of Alzheimer’s type.- Cognitive deterioration and dementia outcome in depression: the search for prognostic factors.- Diagnostic significance of language evaluation in early stages of Alzheimer’s disease.- The Alzheimer patient in the family context: how to help the family to cope.- Towards a clinically specific profile of severe senile primary degenerative dementia of the Alzheimer type (PDDAT).- Sequential clinical approach to differential diagnosis of dementia.- Do old patients with Down’s syndrome develop premature brain atrophy?.- Results of EEG brain mapping and neuroimaging methods in Senile Dementia of Alzheimer’s Typ (SDAT) and Vascular Dementia (VD).- Regulation of EEG delta activity by the cholinergic nucleus basalis.- EEG- and cognitive changes in Alzheimer’s disease — a correlative follow-up study.- Decreased hippocampal metabolic rate in patients with SDAT assessed by positron emission tomography during olfactory memory task.- PET criteria for diagnosis of Alzheimer’s disease and other dementias.- Oxygen metabolism in the degenerative dementias.- Positron emission tomography for differential diagnosis of dementia: a case of familial dementia.- Comparison between cerebral glucose metabolism and late evoked potentials in patients with Alzheimer’s disease.- High resolution regional cerebral blood flow measurements in Alzheimer’s disease and other dementia disorders.- Single photon emission computed tomography (SPECT) in Pick’s disease: two case reports.- In vivo studies of hippocampal atrophy in Alzheimer’s disease.- Outline for theevaluation of nootropic drugs.- Drug treatment of dementia.- Cognitive enhancing properties of antagonist ?-carbolines: new insights into clinical research on the treatment of dementias?.- Long term treatment of SDAT patients with pyritinol.- Listed in Current Contents.