Mathe / Muggia Cancer Chemo- and Immunopharmacology

1. Chemopharmacology
Erscheinungsjahr 2012
ISBN: 978-3-642-81488-4
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 74, 315 Seiten, eBook

Reihe: Recent Results in Cancer Research

Zielgruppe

Research

Autoren/Hrsg.

Mathe, G.

Muggia, F. M.

Inhaltsverzeichnis

General Progress in Clinical Chemotherapy of Advanced Disease.- Adjuvant Therapies of Postsurgical Minimal Residual Disease.- Limits of Animal Models in Cancer Chemotherapy.- Clinical Chemotherapy: Its Correlation with Experimental Models.- Metabolic Conversion of Methotrexate in Man.- Biochemical Control of High-Dose Methotrexate/Leucovorin Rescue Therapy.- High-Dose Methotrexate in Combination Chemotherapy for Small Cell Lung Cancer.- Clinical and Laboratory Reevalution of Dichloromethotrexate.- An Overview of the Clinical Pharmacology of N-Phosphonacetyl-l-Aspartate (PALA), a New Antimetabolite.- N-(Phosphonacetyl)-l-Aspartate (PALA):Current Status.- Synthesis, Biologic Effects, and Biochemical Properties of Some 2’-Azido- and 2’-Amino- 2’-Deoxyarabinofuranosyl Pyrimidines and Purines.- Prediction of Clinical Response to 5-Fluorouracil-Containing Chemotherapy: Preliminary Results of in Vitro Assay in Human Breast Cancer.- Vindesine: A New Vinca Alkaloid.- The Epipodophyllotoxin Derivatives VM-26 and VP-16-213,1976-1979,aReview.- Antitumor Activity, Pharmacology, and Toxicity of Ellipticines, Ellipticinium, and 9-Hydroxy Derivatives: Preliminary Clinical Trials of 2-Methyl-9-Hydroxy Ellipticinium (NSC 264-137).- Comparative Pharmacokinetics of Chlorambucil and Melphalan in Man.- Clinical Implications of Cisplatin Pharmacology.- Cisplatinumdiamminodichloride (CPDD) in Chemotherapy of Cancers: A Phase II Therapeutic Trial.- 1,2-Diaminocyclohexane Platinum Derivatives of Potential Clinical Value.- Preclinical and Phase I Studies of Malonatoplatinum.- A Review of Clinical Studies of Pepleomycin.- Experimental and Clinical Activity of a New Anthracycline Derivative: Detorubicin (14-Diethoxyacetoxydaunorubicin).- Clinical Study of Detorubicin.- Preliminary ClinicalExperience with 4’ -Epidoxorubicin in Advanced Human Neoplasia.- Quelamycin: A Summary of Phase I Clinical Trials.- Current Status of Japanese Studies with the New Anthracycline Antibiotic Aclacinomycin A.- Phase II Trial of Aclacinomycin in Acute Leukemia and Lymphosarcoma.- Ultrastructuralé Study of the Cardiotoxicity and Light- Microscopic Findings of the Skin After Treatment of Golden Hamsters with Seven Different Anthracyclines.- m-AMSA: A New Anticancer Agent.- The Rediscovery of DON (6-Diazo-5-oxo-l-norleucine).- The Use of Peritoneal Dialysis for Delivery of Chemotherapy to Intraperitoneal Malignancies.- The Development of Mesna for the Inhibition of Urotoxic Side Effects of Cyclophosphamide, Ifosfamide, and Other Oxazaphosphorine Cytostatics.- Cell Kinetic Factors, Single Drugs and Combination.- Hyperthermia and Chemotherapy: Preclinical Considerations.- The Disposition of Intraperitoneal Bleomycin, Melphalan, and Vinblastine in Cancer Patients.- Clinical Correlations of Drug Sensitivity in the Human Tumor Stem Cell Assay.- Comments on the Carcinogenic, Mutagenic, and Teratogenic Properties of Anticancer Drugs.- Long-Term Sequelae of Cancer Chemotherapy.