Maresca / Lindquist Heat Shock

Erscheinungsjahr 2012
ISBN: 978-3-642-76679-4
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 320 Seiten, eBook

Zielgruppe

Research

Autoren/Hrsg.

Maresca, Bruno

Lindquist, Susan

Inhaltsverzeichnis

Analysis of Heat Shock Regulation.- Transcriptional Activation of Drosophila Heat Shock Genes.- Structure and Function of Drosophila Heat Shock Factor.- In vivo and in vitro Studies on the Activation and Binding of Human Heat-shock Transcription Factor.- Mechanisms of Regulation of Small Heat Shock Protein Genes in Drosophila.- Heat Shock Protein Functions in E. coli and Yeast.- The Biological Role of the Universally Conserved E. coli Heat Shock Proteins.- E. coli Mutants Lacking the dnaK Heat Shock Gene: Identification of Cellular Defects and Analysis of Suppressor Mutations.- DnaJ and DnaK Heat Shock Proteins Activate Sequence Specific DNA Binding by RepA.- HSP70 Family of Proteins of the Yeast S. cerevisiae.- Ubiquitin-Conjugating Enzymes Mediate Essential Functions of the Stress Response.- Analysis of Heat Shock Protein Functions.- Early Effects of Heat Shock on Enzymes: Heat Denaturation of Reporter Proteins and Activation of a Protein Kinase which Phosphorylates the C-Terminal Domain of RNA Polymerase II.- Interaction of HSP47 with Newly Synthesized Procollagen, and Regulation of HSP Expression.- In vitro Inhibition of Nascent Polypeptide Formation by HSP70 Proteins.- HSP90, a Carrier of Key Proteins that Regulates Cell Function.- Genetic Analysis of Heat Shock Protein Functions in Yeast.- The Stress Response in the Freshwater Polyp Hydra.- Heat Shock Response during Morphogenesis in the Dimorphic Pathogenic Fungus Histoplasma capsulatum.- Effects of Heat Shock on Development and Actin mRNA Stability in Drosophila.- Heat Shock Proteins and Translocations.- Role of HSP60 in Folding/Assembly of Mitochondrial Proteins.- Role of Heat Shock Proteins in Mitochondrial Protein Import.- A Role for the 73-kDa Heat Shock Cognate Protein in a Lysosomal Pathway of Intracellular Protein Degradation.- Immunology.- Immune Recognition of Stress Proteins in Infection and in Surveillance of Stressed Cells.- Heat Shock Proteins and Mycobacterial Infection.- Heat Shock Proteins and Antimicrobial Immunity.- Heat Shock Proteins and Antigen Processing and Presentation.- Recognition of Heterologous and Autologous Stress Protein Sequences by Heat Shock Reactive ??T Lymphocytes.- Expression of Stress Proteins on the Surface of Cells of the Immune System.- Medical Applications of Heat Shock Response.- Quantification of Protein Denaturation with Sulfhydryl Agents: Application to Heat Shock in Mammalian Cells.- Stable Expression of Human HSP70 Gene in Rodent Cells Confers Thermal Resistance.- The Role of HSP90 in Tumor Specific Immunity.- Heat Shock and Oxidative Injury in Human Cells.- Induction of HSP70 Genes in the Mammalian Nervous System by Hyperthermia, Tissue Injury and Other Traumatic Events.- Ubiquitin and the Lysosomal System: Molecular Pathological and Experimental Findings.