Paramagnetism in Experimental Biomolecular NMR

Erscheinungsjahr 2018
ISBN: 978-1-78801-086-3
Verlag: RSC Publishing

Buch, Englisch, 340 Seiten, Format (B × H): 165 mm x 234 mm, Gewicht: 635 g

Paramagnetic NMR is a growing technique that represents an increasingly important tool for the investigation of biomolecules. This book presents an update and overview of the paramagnetic NMR phenomena and effects as well as guidelines for practical implementation of state-of-the-art experiments. All experiments are supported by a solid theoretical foundation. Areas mentioned are the development of solid state NMR, the use of paramagnetic tags providing information on the structure and mobility of the investigated systems, and dynamic nuclear polarization to increase sensitivity.

Compiled by experts in the field, this book has international appeal for researchers as well as students interested in magnetic resonance and structural biology who require experimental support and accessible information.

Autoren/Hrsg.

Luchinat, Claudio

Parigi, Giacomo

Ravera, Enrico

Fachgebiete

• Naturwissenschaften Physik Angewandte Physik Biophysik
• Naturwissenschaften Biowissenschaften Angewandte Biologie Biophysik
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Bildgebende Verfahren, Nuklearmedizin, Strahlentherapie Magnetresonanztomographie, Computertomographie (MRT, CT)

Inhaltsverzeichnis

NMR Consequences of the Nucleus-Electron Spin Interactions;

Intrinsic and Extrinsic Paramagnetic Probes;

Structural and Dynamic Characterization of Protein Domains Using Paramagnetic Data;

Treating Biomacromolecular Conformational Variability;

Protein-Protein Interactions;

Solid-State NMR of Paramagnetic Proteins;

Relaxometry and Contrast Agents;

Dynamic Nuclear Polarization;

Paramagnetic NMR in Drug Discovery;

Small Paramagnetic Co-solute Molecules;

Subject Index