Catalytic Asymmetric Radical Reactions

1. Auflage 2025
ISBN: 978-3-527-35028-5
Verlag: Wiley-VCH GmbH

Buch, Englisch, 560 Seiten, Format (B × H): 171 mm x 245 mm, Gewicht: 1176 g

Strategies to develop catalytic asymmetric radical reactions, from metal-based methods to organocatalytic systems
 
Catalytic Asymmetric Radical Reactions systematically and comprehensively summarizes the development of different strategies to realize asymmetric radical reactions, from metal-based methods to organocatalytic systems.
 
The book starts with the background introduction of this topic and emphasizes the significance and challenge of the stereocontrol over the radical intermediates. Subsequently, it describes the detailed strategies to realize the asymmetric radical reactions, demonstrating how the design of chiral catalysts and substrates helps to achieve the asymmetric induction. Finally, it summarizes the developed strategies and presents a perspective in future development of asymmetric radical reactions.
 
Catalytic Asymmetric Radical Reactions includes information on:
 
* Earth-abundant transition metal (e.g., iron, cobalt, nickel, copper, and manganese)-catalyzed asymmetric radical reactions
* Photoredox/earth-abundant metal-catalyzed asymmetric radical reactions and precious transition metal-catalyzed asymmetric radical reactions
* Chiral Lewis acid-catalyzed asymmetric radical transformations and chiral-at-metal complex-catalyzed asymmetric radical reactions
* Organocatalysis via covalent bonds and hydrogen bonding for asymmetric radical transformations
* Covalent interaction (S/Sn/B-centered radical)-induced asymmetric radical reactions
 
Catalytic Asymmetric Radical Reactions is a timely reference for researchers in academia and industry working in the fields of organic synthesis, drug discovery, and materials science.

Autoren/Hrsg.

Liu, Xin-Yuan

Liu, Guosheng

Fachgebiete

• Naturwissenschaften Chemie Physikalische Chemie Chemische Reaktionen, Katalyse
• Naturwissenschaften Chemie Organische Chemie
• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie

Inhaltsverzeichnis

1 Iron-Catalyzed Radical Asymmetric Reactions
2 Cobalt-Catalyzed Asymmetric Radical Reactions
3 Nickel-Catalyzed Electrophile-Nucleophile and Related Asymmetric Radical Cross-Coupling
4 Nickel-Catalyzed Asymmetric Cross-Electrophile Couplings and Related Asymmetric Radical Cross-Coupling
5 Copper-Catalyzed Oxidative Asymmetric Radical Cross-Coupling of C(sp3)-H Bonds
6 Copper-Catalyzed Enantioconvergent Radical Cross-Coupling under Thermal Conditions
7 Manganese-Catalyzed Asymmetric Radical Reactions
8 Photoredox/Earth-Abundant Metal-Catalyzed Asymmetric Radical Reactions
9 Precious Transition Metal-Catalyzed Asymmetric Radical Reactions
10 Chiral Lewis Acid-Catalyzed Asymmetric Radical Transformations
11 Chiral-at-Metal Complex-Catalyzed Asymmetric Radical Reactions
12 Chiral Photochemical Reactions in Supramolecular Assemblies
13 Organocatalysis via Covalent Bonds for Asymmetric Radical Transformations
14 Organocatalysis via Hydrogen-bonding for Asymmetric Radical Transformations
15 Covalent Interaction (S/Sn/B-Centered Radical)-Induced Asymmetric Radical Reactions

Über Autor(innen)

Xin-Yuan Liu is a Chair Professor in the Department of Chemistry at Southern University of Science and Technology, China. He focuses on developing novel chiral anionic ligands in realizing the copper-catalyzed asymmetric radical reactions Currently, he is an associated editor of Synthesis. He has received numerous scientific awards, including the National Distinguished Young Scholar (NSFC), XPLORER prize, Boehringer Ingelheim Lectureship (Boston College), CAPA Distinguished Faculty Award, the Distinguished Lectureship Award from the Chemical Society of Japan, and The 12th CCS-BASF Youth Knowledge Innovation Award.

Guosheng Liu is a Professor in Shanghai Institute of Organic Chemistry (SIOC), Chinese Academy of Sciences (CAS), China. His research focuses on the highly selective functionalization of alkenes and alkanes, particularly on the site- and enantioselective sp3 C-H functionalization via metal-catalyzed radical relay. Currently, he is an associated editor of Organic Letters. He has received many scientific awards, including the National Distinguished Young Scholar (NSFC), New Cornerstone Investigator Program, Friedrich Wilhelm Bessel Research Award (Alexander von Humboldt Foundation), and The 9th CCS-BASF Youth Knowledge Innovation Award.