Microscopy of the Heart

1. Auflage 2018
ISBN: 978-3-319-95302-1
Verlag: Springer International Publishing

Buch, Englisch, 132 Seiten, HC runder Rücken kaschiert, Format (B × H): 160 mm x 241 mm, Gewicht: 409 g

This book provides in depths information on different microscopy approaches and supplies the reader with methods how to untangle highly complex processes involved in physiological and pathophysiological cardiac signaling. Microscopy approaches have established themselves as the quasi gold standard that enables us to appreciate the underlying mechanisms of physiological and pathophysiological cardiac signaling. This book presents the most important microscopy techniques from the level of individual molecule e.g. Förster-Resonance Energy Transfer (FRET), up to cellular and tissue imaging, e.g. electron microscopy (TEM) or light sheet microscopy. The book is intended for graduate students and postdocs in cardiovascular research, imaging and cell biology, pre-clinical and clinical researchers in cardiovascular sciences as well as decision makers of the pharmaceutical industry.

Zielgruppe

Research

Autoren/Hrsg.

Lipp, Peter

Kaestner, Lars

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Kardiologie, Angiologie, Phlebologie
• Naturwissenschaften Biowissenschaften Zellbiologie
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Bildgebende Verfahren, Nuklearmedizin, Strahlentherapie Radiologie, Bildgebende Verfahren
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie

Inhaltsverzeichnis

1. Genetically encoded fluorescent sensors.- 2. Small molecule dyes or action.- 3. Potential.- 4. Recordings.- 5. Superresolution measurements.- 6. Fluorescence.- 7. Lifetime imaging.- 8. Caged compounds.- 9. Confocal imaging.- 10. FRET and quantitative FRET.- 11. Scanning probe imaging.- 12. Atomic force microscopy.- 13. Ion conductance scanning.- 14. SNOM.- 15. Sonography/echocardiography.- 16. Magnetic resonance imaging (MRI).- 17. PET & fPET.

Über Autor(innen)

Lars Kaestner PhD, is principal investigator at Theoretical Medicine and Biosciences, Saarland University, Homburg, and Experimental Physics, Saarland University, Saarbrücken, Germany. He studies basic cellular mechanisms of the circulation (heart and red blood cells) using newest imaging methods

Peter Lipp is Professor and Head of the Institute for Molecular Cell Biology, Saarland University, in Homburg, Germany. The main focus of his institute lies on studying basic cellular mechanisms of the heart in its clinical context, with the aim to develop new therapies and treatment strategies.