Animal Cell Technology: From Target to Market

Proceedings of the 17th ESACT Meeting Tylösand, Sweden, June 10-14, 2001
2001
ISBN: 978-1-4020-0264-9
Verlag: Springer Netherlands

Buch, Englisch, Band 1, 595 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 1168 g

Reihe: ESACT Proceedings

This book is the lasting product, a resource of up-to-date information in the scientific literature for the field of animal cell technology, as it was presented during a pleasant and stimulating meeting in Tylösand, Sweden, in June 2001. The title of the meeting, From Target to Market, indicates the usefulness of Animal Cell Technology during all steps in the pharmaceutical development process. Following the biotech products reaching the market, it shows an upward trend in the contribution of biotech products to total New Molecular Entity output in the nineties, which continued until 1996 when biotech represented 25% of the annual output. Since then the proportion has been decreasing.
A perceived hurdle from a market perspective is that a protein per definition is biodegradable and thus requires intravenous, or for some drugs subcutaneous administration. New promising administration technologies such as pulmonary delivery were highlighted at this meeting.
The emphasis on project selection prior to entry in the development phase has triggered a portfolio management using more extensive preclinical data before a development decision is taken. Animal cells have become a very important tool in the drug discovery process. The next generation of products will evolve from applications such as gene therapy, novel vaccines, cell therapy, and gene regulation.
Animal cell technology has a major role to play in the post-sequence era.

Zielgruppe

Research

Autoren/Hrsg.

Lindner-Olsson, E.

Lüllau, E.

Chatzissavidou, N.

Fachgebiete

• Naturwissenschaften Biowissenschaften Tierkunde / Zoologie Tierethologie
• Naturwissenschaften Biowissenschaften Zellbiologie
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie

Inhaltsverzeichnis

17th ESACT Meeting Committees. ESACT Executive Committee. Sponsors. Companies Participating in the Trade Exhibition. List of Participants. Introduction - From Target to Market. Acknowledgements. I. Identification of Drugs and Drug Targets. II. Expression Systems for Target and Drug Production. III. Cell Physiology and Metabolism. IV. Process Technology. V. Changes in Regulatory Environment. VI. New Technologies for Administration of Cell Derived Proteins. VII. Novel Prophylactic and Therapeutic Approaches Based on Animal Cells or Nucleic Acids. Author Index. Subject Index.