Li Adaptive Radiation Therapy

Erscheinungsjahr 2011
ISBN: 978-1-4398-1635-6
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 426 Seiten

Modern medical imaging and radiation therapy technologies are so complex and computer driven that it is difficult for physicians and technologists to know exactly what is happening at the point-of-care. Medical physicists responsible for filling this gap in knowledge must stay abreast of the latest advances at the intersection of medical imaging and radiation therapy. This book provides medical physicists and radiation oncologists current and relevant information on Adaptive Radiation Therapy (ART), a state-of-the-art approach that uses a feedback process to account for patient-specific anatomic and/or biological changes, thus delivering highly individualized radiation therapy for cancer patients. The book should also benefit medical dosimetrists and radiation therapists.

Adaptive Radiation Therapy describes technological and methodological advances in the field of ART, as well as initial clinical experiences using ART for selected anatomic sites. Divided into three sections (radiobiological basis, current technologies, and clinical applications), the book covers:

- Morphological and biological biomarkers for patient-specific planning

- Design and optimization of treatment plans

- Delivery of IMRT and IGRT intervention methodologies of ART

- Management of intrafraction variations, particularly with respiratory motion

- Quality assurance needed to ensure the safe delivery of ART

- ART applications in several common cancer types / anatomic sites

The technology and methodology for ART have advanced significantly in the last few years and accumulated clinical data have demonstrated the need for ART in clinical settings, assisted by the wide application of intensity modulated radiation therapy (IMRT) and image-guided radiation therapy (IGRT). This book shows the real potential for supplying every patient with individualized radiation therapy that is maximally accurate and precise.

Zielgruppe

Medical physicists, radiation oncologists, dosimetrists, and graduate students.

Autoren/Hrsg.

Li, X. Allen

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Bildgebende Verfahren, Nuklearmedizin, Strahlentherapie Radiologie, Bildgebende Verfahren
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Bildgebende Verfahren, Nuklearmedizin, Strahlentherapie Nuklearmedizin, PET, Radiotherapie

Inhaltsverzeichnis

Contents
Series Preface
Foreword
Preface
Acknowledgments
Editor
Contributors

Section I Treatment Planning
Radiobiological Principles for Adaptive Radiotherapy, Joseph O. Deasy and Jeho Jeong
Three- and Four-Dimensional Morphological Imaging for Adaptive Radiation Therapy Planning, Lei Xing, Jianguo Qian, Kihwan Choi, and Tae-Suk Suh
Biological Imaging for Adaptive Radiation Therapy, Robert Jeraj and Matt Nyflot
Biomarkers of Early Response for Adaptive Radiation Therapy, Issam El Naqa, Jeffrey M. Craft, Jung Hun Oh, and Joseph O. Deasy
Treatment Plan Optimization for Adaptive Radiation Therapy, Qiuwen Wu, Justus Adamson, and Qingrong Jackie Wu
Treatment Planning Using Biologically Based Models, Vladimir A. Semenenko and X. Allen Li
Isoeffect Calculations in Adaptive Radiation Therapy and Treatment Individualization, Robert D. Stewart, Joo Han Park, and David J. Carlson

Section II Treatment Delivery
Delivery of Intensity-Modulated Radiation Therapy, Cedric X. Yu
Computed Tomography-Based Image-Guided Radiation Therapy Technology, Uwe Oelfke and Simeon Nill
Non-Computed Tomography–Based Image-Guided Radiation Therapy Technology, David Shepard, Daliang Cao, Jianzhou Wu, Jian-Yue Jin, Chad Lee, and Douglas Miller
Off line Plan Adaptation Strategies, James Balter and Dan McShan
Online Adaptive Correction Strategies for Interfraction Variations, Ergun Ahunbay and X. Allen Li
Intrafraction Variations and Management Technologies, Laura I. Cerviño and Steve B. Jiang
Methods for Real-Time Tumor Position Monitoring and Radiotherapy Tracking, Paul Keall
Quality Assurance in Adaptive Radiation Therapy, Zheng Chang, Jennifer O’Daniel, and Fang-Fang Yin

Section III Clinical Applications
Promises of Functional Imaging for Adaptive Radiation Therapy of Central Nervous System Tumors, Yue Cao
Adaptive Radiation Therapy for Head and Neck Cancer, Lei Dong and David L. Schwartz
Adaptive Radiation Therapy for Breast Cancer, Kristofer Kainz, X. Allen Li, and Julia White
Adaptive Radiation Therapy for Lung Cancer, Jun Lian and Lawrence B. Marks
Adaptive Radiation Therapy for Liver Cancer, An Tai, X. Allen Li, and Laura A. Dawson
Adaptive Radiation Therapy for Prostate Cancer, C.-M. Charlie Ma
Adaptive Radiation Therapy for Gynecologic Cancers, Beth Erickson, Karen Lim, James Stewart, Eric Donnelly, William Small, Anthony Fyles, and Michael Milosevic
Adaptive Radiotherapy for Treatment of Soft-Tissue Sarcoma, Julie A. Bradley, Kristofer Kainz, X. Allen Li, Thomas F. DeLaney, and Dian Wang

Index