Buch, Englisch, 532 Seiten, Previously published in hardcover, Format (B × H): 155 mm x 235 mm, Gewicht: 832 g
Biophysics of Molecular Excitability
Buch, Englisch, 532 Seiten, Previously published in hardcover, Format (B × H): 155 mm x 235 mm, Gewicht: 832 g
ISBN: 978-90-481-7384-6
Verlag: Springer Netherlands
The goal of this book is to explore the complexity of a microscopic bit of matter that exists in a myriad of copies within our bodies, the voltage-sensitive ion channel. We seek to investigate the way in which these macromolecules make it possible for the long fibers of our nerve and muscle cells to conduct impulses. These integral components of cell membranes are marvels of nature's evolutionary adaptation. To understand them we must probe the boundaries of physics and chemistry. Since function is intimately related to structure, we examine the molecular structure of channels, focusing on physical principles that govern all matter. With the application of genetic methods, our knowledge of ion channels has broadened and deepened. In the hope that research can help ameliorate suffering, we discuss the diseases that arise from channel malfunctions due to genetic mutations. This book is intended for students and scientists who are willing to travel into uncharted waters of an interdisciplinary science. We approach the subject of volta- sensitive ion channels from various points of view. This book seeks to give voice to the viewpoints of the physical and the biological scientist, and to bridge gaps in terminology and background. Readers may find this book to have both elementary and advanced aspects: For the reader trained in the biological sciences, it reviews background in physics and chemistry; for the reader trained in the physical sciences, it reviews background in physiology and biochemistry.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Naturwissenschaften Physik Angewandte Physik Biophysik
- Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
- Naturwissenschaften Biowissenschaften Tierkunde / Zoologie Tierphysiologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft
- Naturwissenschaften Physik Thermodynamik Festkörperphysik, Kondensierte Materie
- Naturwissenschaften Biowissenschaften Angewandte Biologie Biophysik
- Naturwissenschaften Biowissenschaften Biowissenschaften Neurobiologie, Verhaltensbiologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
Weitere Infos & Material
Exploring Excitability.- Information In The Living Body.- Animal Electricity.- Electrophysiology Of The Axon.- Aspects Of Condensed Matter.- Ions In The Electric Field.- Ions Drift And Diffuse.- Multi-Ion And Transient Electrodiffusion.- Models Of Membrane Excitability.- Admittance To The Semicircle.- What's That Noise?.- Ion Channels, Proteins And Transitions.- Diversity And Structures Of Ion Channels.- Microscopic Models Of Channel Function.- Order From Disorder.- Polar Phases.- Delicate Phases And Their Transitions.- Propagation And Percolation In A Channel.- Screws And Helices.- Voltage-Induced Gating Of Ion Channels.- Branching Out.
