An Introduction to Bioinformatics

2. Auflage 2005
ISBN: 978-0-19-927787-2
Verlag: Oxford University Press

Buch, Englisch, 376 Seiten, Format (B × H): 189 mm x 246 mm

Maintains lucid style and clarity of explanations for which the author is renowned, making the subject truly accessible to a wide range of students
Rich pedagogy includes many exercises, problems, and WebLems to encourage students to explore the subject for themselves
Careful balance between biology and computer science: introduces those aspects of computer science which underpin the discipline, without demanding detailed prior knowledge
Companion web site includes figures from the book available to download, to facilitate lecture preparation, and a variety of interactive resources, including web links, 3D structures, and data sets, to support and encourage hands-on learning by the student

New to this edition
New chapter on proteomics and systems biology, reflecting current advances in microarray analysis, and genomic and proteomic databases

New chapter on drug discovery and design, expanding the coverage offered by the first edition
Coverage of JAVA-based programming to complement the treatment of PERL
New two-colour text design
Links to the SCOP database for all structures cited in the book, facilitating access to 3D representations of these structures
Answers to exercises provided at the end of the book

Written by a pioneer of the use of bioinformatics in research, Introduction to Bioinformatics 2/e introduces the student to the power of bioinformatics as a set of scientific tools. The book explains how to access the data archives of genomes and proteins, and the kind of questions these data and tools can answer - how to make inferences from the data archives, to make connections among them, and to derive useful and interesting predictions.

Contents

1 Introduction
2 Genome Organization and Evolution
3 Archives and Information Retrieval
4 Alignments and Phylogentic Trees
5 Protein Structure and Drug Discovery
6 Proteomics and Systems Biology

Zielgruppe

Second and final year biomolecular science undergraduate students as well as those studying an MSc in this field.

Autoren/Hrsg.

Lesk, Arthur M.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik
• Naturwissenschaften Biowissenschaften Molekularbiologie
• Mathematik | Informatik EDV | Informatik Informatik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizinische Mathematik & Informatik
• Naturwissenschaften Biowissenschaften Biowissenschaften
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)

Über Autor(innen)

Arthur Lesk, Professor of Biochemistry and Molecular Biology, The Pennsylvania State University, USA