Buch, Englisch, 120 Seiten, Format (B × H): 148 mm x 210 mm
Buch, Englisch, 120 Seiten, Format (B × H): 148 mm x 210 mm
ISBN: 978-3-89967-786-7
Verlag: Pabst Science Publishers
Intravital imaging of the microcirculation represents a scientific method bridging the gap between molecular microvascular research and clinical studies. Imaging devices includes intravital microscopy (IVM) and related technologies (e.g., Sidestream Dark-Field Imaging – SDF). Potential fields of research are inflammation, cancer angiogenesis, arteriosclerosis and others. Recent IVM work showed that immune cell responses to antigens in situ are different from those observed in vitro and appear to be dictated by factors uniquely relevant to the micro-environment of the intact organs. IVM can potentially generate new discoveries and serve as a “reality check” for areas of research that were formerly the exclusive domain of in vitro experimentation. Moreover, using new generation intravital molecular imaging microscopy it is possible for the first time to visualize directly specific pathological processes and to explain more in detail pharmacological mechanisms. Especially the SDF method provides the tools for translational research from the bench to the bedside for a variety of organs. This book describes intravital microcirculation imaging of the brain, liver, intestine, joints, sublingual area and the eye. It is intended as a compendium for preclinical and clinical microcirculatory experimentation. It includes not only experimental techniques but also examples for scientific projects that can be performed using the specific methods. Therefore, it will be a valuable reference guide for basic researchers as well as for clinical scientists.
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Kardiologie, Angiologie, Phlebologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete AINS Intensivmedizin
Weitere Infos & Material
Foreword
Dragan Pavlovic – Greifswald, Germany
Vascular access and tracheostomy
James Toguri, Mandana Kianian – Halifax, Canada
Intestinal microcirculation
Mandana Kianian, Christian Lehmann – Halifax, Canada
Mesenteric microcirculation
Jules Rippke, Michael Borowiak – Greifswald, Germany
Iris microcirculation
Melanie Kelly, James Toguri – Halifax, Canada
Joint microcirculation
Jason McDougall – Halifax, Canada
Brain microcirculation
Juan Zhou – Halifax, Canada
Liver microcirculation
Zdenek Turek, V. Cerny – Prague, Czech Republic
Sublingual microcirculation
Vladimir Cerny – Hradec Kralove, Czech Republic
Christian Lehmann – Halifax, Canada
