Buch, Englisch, 412 Seiten, Format (B × H): 216 mm x 279 mm, Gewicht: 1320 g
Buch, Englisch, 412 Seiten, Format (B × H): 216 mm x 279 mm, Gewicht: 1320 g
ISBN: 978-1-55581-439-7
Verlag: ASM Press
Captures the state of the science with twenty reviews that examine the latest in today’s antiviral drug discovery efforts.
Presents the fundamental principles of antiviral agents and forecasts future possibilities.
Investigates novel enzyme and protein inhibitors.
Analyzes clinical aspects of viral infection with regard to treatment and toxicity.
Examines known and potential targets at all stages of viral development.
Serves as a resource for virologists, biochemists, pharmaceutical chemists, and other investigators.
Covers a broad range of viruses, including HIV-1, HSV, and HCV.
This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.
Autoren/Hrsg.
Weitere Infos & Material
Table of Contents
1. Antiherpesviral DNA Polymerase Inhibitors
Donald M. Coen
2. Entry Inhibitors of Human Immunodeficiency Virus
Masanori Baba
3. Human Immunodeficiency Virus Type 1 Non-Nucleoside Reverse Transcriptase Inhibitors
Dirk Jochmans, Johan Vingerhoets, Eric Arnoult, Luc Geeraert, and Jérôme Guillemont
4. Nucleoside Analogue Inhibitors of Human Immunodeficiency Virus Reverse Transcriptase
Jérôme Deval and Matthias Götte
5. Integrase as a Novel Target for the Inhibition of Human Immunodeficiency Virus Type 1 Infection: Current Status and Future Perspectives
Linos P.R. Vandekerckhove, Frauke Christ, Zeger Debyser, Andrew Owen, David Back, Arnout Voet, Jonathan Schapiro, and Dirk Vogelaers
6. Human Immunodeficiency Virus Type 1 Tat and Rev as Potential Targets for Drug Development
Sergei Nekhai and Kuan-Teh Jeang
7. Inhibitors of the Human Immunodeficiency Virus Protease
Jorge L. Martinez-Cajas and Mark A. Wainberg
8. Hepatitis C Virus RNA-Dependent RNA Polymerase as a Target for Antiviral Drug Intervention: Non-Nucleoside Inhibitors
Yaya Liu, Yupeng He, and Akhteruzzaman Molla
9. Nucleoside Analog Inhibitors of Hepatitis C Viral Replication
Steven S. Carroll and Robert L. LaFemina
10. Antiviral Targets in Orthopoxviruses
Mark N. Prichard and Earl R. Kern
11. Influenza Virus Antiviral Targets
Gillian M. Air and Wayne J. Brouillette
12. Developments in the Search for Small Molecule Inhibitors for Treatment of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)
Dale L. Barnard and Yohichi Kumaki
13. Antiviral Treatment of Flaviviruses
Justin G. Julander
14. Clinical Aspects of Hepatitis C Virus Infection
David Durantel and Fabien Zoulim
15. Microbicides: Molecular Strategies for Prevention of Sexually Transmitted Viral Disease
Raina N. Fichorova
16. Phenotypic Susceptibility Assays for Human Immunodeficiency Virus Type 1
Neil T. Parkin, Eoin Coakley, and Christos J. Petropoulos
17. Metabolism of Antiviral Nucleosides and Nucleotides
Adrian S. Ray and Michael J. M. Hitchcock
18. Targeting the Interferon Response for Antiviral Therapy
Michael D. Robek
19. Toll-Like Receptors: Novel Molecular Targets for Antiviral Immunotherapy
Raymund R. Razonable, Albert J. Eid, and Martin Henault
20. New Herpes Simplex Virus Replication Targets
Sandra K. Weller
Afterword: Closing Thoughts
Robert L. LaFemina
