E-Book, Englisch, 224 Seiten
Koch The Bacteria: Their Origin, Structure, Function and Antibiosis
1. Auflage 2007
ISBN: 978-1-4020-3206-6
Verlag: Springer Netherlands
Format: PDF
Kopierschutz: 1 - PDF Watermark
E-Book, Englisch, 224 Seiten
ISBN: 978-1-4020-3206-6
Verlag: Springer Netherlands
Format: PDF
Kopierschutz: 1 - PDF Watermark
Understanding antibiotic chemotherapy at the ecological level is necessary for more permanent advances in development and in the usage of antibiotic agents. This book traces the history of bacteria, from the development of life on earth to the evolution of diversity. It is this diversity that led, almost automatically to the development of pathogens as well as antibiotics. If we are to create long term antibiotics we must design them with this history in mind.
Autoren/Hrsg.
Weitere Infos & Material
1;Table of Contents;5
2;Preface;7
3;Legend to the Frontispiece: The Structural Elements of the Bacterial Wall: Five Disaccharide Penta- muropeptides Forming a Glycan Chain and Two about to Form a Nona- muropeptide;9
4;Part 1 Origin of Bacteria;12
4.1;1 The Origin of Life Based on Physical Principles;13
4.2;2 Preamble to Life;19
4.3;3 The First Cell;25
4.4;4 Development of Cell Physiology and Diversity;31
5;Part 2 Wall Structure;48
5.1;5 Covalent Bonds and Tensile Strength of Materials;49
5.2;6 Structure of the Fabric that Covers a Bacterium;59
5.3;7 The Covalently Linked Sacculus: the Nona- Muropeptide Model;71
5.4;8 The Structure of the Tessera; the Unit Structure of Murein Wall81
5.5;9 Extrusion and Incorporation into Wall;87
5.6;10 The Role of Poles in the Growth Strategy of Bacteria;91
6;Part 3 Bacterial Morphologies;99
6.1;11 Sidewalls of Gram-Negative Rod-Shaped Bacteria;101
6.2;12 Growth Strategies for Gram-Positive Cells;109
6.3;13 Wall Growth Strategies for Gram-Negative Cells;119
6.4;14 Commas, Vibrios, Spirilla, and Helicobacters; Tapered and Branched Bacteria129
6.5;15 Spirochetes and Spiroplasma and the Special Strategies for CWD ( Cell Wall De . cient) Cells;147
6.6;16 Coccal Versus Rod-Shaped Cells, and the First Bacterium;157
6.7;17 Diseases: Old and New;171
7;Part 4 Antibiosis;190
7.1;18 Lysozymes as Alternatives to ß-lactamsAntibiotics Acting on the Bacterial Wall;191
7.2;19 Development of Wall Antibioics and Bacterial Counter- Measures;195
7.3;20 Antibiotics and Resistance, with an Emphasis on Aminoglycosides;211
7.4;21 Future Chemotherapy Aimed at the Bacterial Murein;219
8;References;227
