King / Gee Multiscale Modeling of Particle Interactions

Applications in Biology and Nanotechnology
1. Auflage 2010
ISBN: 978-0-470-57982-4
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 352 Seiten, E-Book

Discover how the latest computational tools are building ourunderstanding of particle interactions and leading to newapplications
With this book as their guide, readers will gain a newappreciation of the critical role that particle interactions playin advancing research and developing new applications in thebiological sciences, chemical engineering, toxicology, medicine,and manufacturing technology The book explores particles ranging insize from cations to whole cells to tissues and processedmaterials. A focus on recreating complex, real-world dynamicalsystems helps readers gain a deeper understanding of cell andtissue mechanics, theoretical aspects of multiscale modeling, andthe latest applications in biology and nanotechnology.
Following an introductory chapter, Multiscale Modeling ofParticle Interactions is divided into two parts:
Part I, Applications in Nanotechnology, covers:
* Multiscale modeling of nanoscale aggregation phenomena:applications in semiconductor materials processing
* Multiscale modeling of rare events in self-assembled systems
* Continuum description of atomic sheets
* Coulombic dragging and mechanical propelling of molecules innanofluidic systems
* Molecular dynamics modeling of nanodroplets andnanoparticles
* Modeling the interactions between compliant microcapsules andpatterned surfaces
Part II, Applications in Biology, covers:
* Coarse-grained and multiscale simulations of lipid bilayers
* Stochastic approach to biochemical kinetics
* In silico modeling of angiogenesis at multiple scales
* Large-scale simulation of blood flow in microvessels
* Molecular to multicellular deformation during adhesion of immunecells under flow
Each article was contributed by one or more leading experts andpioneers in the field. All readers, from chemists and biologists toengineers and students, will gain new insights into how the latesttools in computational science can improve our understanding ofparticle interactions and support the development of novelapplications across the broad spectrum of disciplines in biologyand nanotechnology.

Autoren/Hrsg.

King, Michael

Gee, David

Inhaltsverzeichnis

CONTRIBUTORS.
1 Introduction (Michael R. King and David J. Gee).
PART I: APPLICATIONS IN NANOTECHNOLOGY.
2 Multiscale Modeling of Nanoscale Aggregation Phenomena:Applications in Semiconductor Materials Processing (TalidSinno).
3 Multiscale Modeling of Rare Events in Self-Assembled Systems(Dmitry I. Kopelevich).
4 Continuum Description of Atomic Sheets (ConstantinePozrikidis).
5 Coulombic Dragging and Mechanical Propelling of Molecules inNanofluidic Systems (Petr Král and Boyang Wang).
6 Molecular Dynamics Modeling of Nanodroplets and Nanoparticles(D. Lussier, N.M.P. Kakalis, and Y. T. Ventikos).
7 Modeling the Interactions Between Compliant Microcapsules andPatterned Surfaces (Anna C. Balazs and AlexanderAlexeev).
PART II: APPLICATIONS IN BIOLOGY.
8 Coarse-Grained and Multiscale Simulations of Lipid Bilayers(Harry A. Stern).
9 Stochastic Approach to Biochemical Kinetics (Ian J.Laurenzi).
10 In Silico Modeling of Angiogenesis at Multiple Scales: FromNanoscale to Organ System (Amina A. Qutub, Feilim Mac Gabhann,Emmanouil D. Karagiannis, and Aleksander S. Popel).
11 Large-Scale Simulation of Blood Flow in Microvessels(Prosenjit Bagchi).
12 Molecular to Multicellular Deformation During Adhesion ofImmune Cells Under Flow (David J. Gee and Michael R.King).
INDEX.

Über Autor(innen)

MICHAEL R. KING, PhD, is an Associate Professor ofBiomedical Engineering at Cornell University. King is an expert onthe receptor-mediated adhesion of circulating cells, and hasdeveloped new computational and in vitro models to study thefunction of leukocytes, platelets, and stem, stem and cancer cellsunder flow. He is a former Whitaker investigator, a James D. WatsonInvestigator of New York State, and an NSF CAREER Award recipient.King received the 2008 ICNMM Outstanding Researcher Award from theAmerican Society of Mechanical Engineers, was the 2007-2008Professor of the Year in Engineering at the University ofRochester, and received the 2009 Outstanding Contribution for aPublication in the international journal Clinical Chemistry.
DAVID J. GEE, PhD, is an Assistant Professor ofMechanical Engineering at the Rochester Institute of Technology,where he studies the inflammatory response and investigatesapplications in receptor-mediated adhesion. Previously, Dr. Gee wasa research assistant professor and postdoctoral fellow in theDepartment of Biomedical Engineering at the University ofRochester, where he studied inflammation, and has also served as aresearch engineer at the Institute for Advanced Technology at TheUniversity of Texas at Austin, where he specialized in impactmechanics and computational solid mechanics.