Williams Hematology, 9e

9. Auflage 2015
ISBN: 978-0-07-183300-4
Verlag: MCGRAW HILL EDUCATION & MEDIC

Buch, Englisch, 2528 Seiten, Format (B × H): 220 mm x 282 mm, Gewicht: 4511 g

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.The world's most highly regarded reference text on the mechanisms and clinical management of blood diseasesA Doody's Core Title for 2020!Edition after edition, Williams Hematology has guided generations of clinicians, biomedical researchers, and trainees in many disciplines through the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood cells and coagulation proteins. It is acknowledged worldwide as the leading hematology resource, with editors who are internationally regarded for their research and clinical achievements and authors who are luminaries in their fields.The Ninth Edition of Williams Hematology is extensively revised to reflect the latest advancements in basic science, translational pathophysiology, and clinical practice. In addition to completely new chapters, it features a full-color presentation that includes 700 photographs, 300 of which are new to this edition, and 475 illustrations. Recognizing that blood and marrow cell morphology is at the heart of diagnostic hematology, informative color images of the relevant disease topics are conveniently integrated into each chapter, allowing easy access to illustrations of cell morphology important to diagnosis.Comprehensive in its depth and breath, this go-to textbook begins with the evaluation of the patient and progresses to the molecular and cellular underpinnings of normal and pathological hematology. Subsequent sections present disorders of the erythrocyte, granulocytes and monocytes, lymphocytes and plasma cells, malignant myeloid and lymphoid diseases, hemostasis and thrombosis, and transfusion medicine.

Autoren/Hrsg.

Kaushansky, Kenneth

Lichtman, Marshall A.

Prchal, Josef

Levi, Marcel

Press, Oliver

Burns, Linda

Caligiuri, Michael

Inhaltsverzeichnis

1Initial approach to the patient: History and physical examination2Examination of blood cells3Examination of the marrow4Consultative Hematology5Structure of the marrow and hematopoietic microenvironment6The organization and structure of lymphoid tissues7Hematology of the fetus and newborn8Hematology during pregnancy9Hematology in older persons10Genetic principles11Genomics 12Epigenetics 13Cytogenetic and Genetic Abnormalities14Metabolism of Hematological Neoplastic Cells15Apoptosis and Autophagy16Cell cycle regulation and hematological disorders17Signal transduction pathways18Hematopoietic stem cells, progenitors, and cytokines19The inflammatory response20Innate immunity21Adaptive immunity22Pharmacology and toxicity of antineoplastic drugs23Hematopoietic stem cell transplantation24Treatment of infections in the immunocompromised host 25Antithrombotic therapy26Immune cell therapy27Vaccine therapy 28Therapeutic apheresis: indications, efficacy, and complications 29Gene transfer for therapy 30Regenerative Medicine: Multipotential cell therapy for tissue replacement 31Structure and Composition of the ErythrocyteAbsorb former 30 Composition of Erythrocyte.32Erythropoiesis 33Erythrocytes turnover 34Clinical manifestations and classification of erythrocyte disorders35Aplastic anemia 36Pure red cell aplasia37Anemia of chronic disease38Erythropoietic effects of endocrine disorders 39The congenital dyserythropoietic anemias40Paroxysmal nocturnal hemoglobinuria41Folate, cobalamin and megaloblastic anemias42Iron Metabolism 43Iron deficiency and overload44Anemia resulting from other nutritional deficiencies

Über Autor(innen)

Lichtman, Marshall A.
Marshall Lichtman, M.D.Professor of MedicineUniversity of Rochester School of MedicineRochester, NY

Levi, Marcel
Chairman, Department of MedicineAcademic Medical CenterUniversity of AmsterdamAmsterdam, The Netherlands

Prchal, Josef
Professor of Medicine, Pathology, and Genetics Hematology Division University of Utah Salt Lake City, Utah Department of Pathophysiology First Faculty of Medicine Charles University in Prague Czech Republic

Kaushansky, Kenneth
Senior Vice President, Health Sciences Dean, School of Medicine Stony Brook University Stony Brook, NY

Kenneth Kaushansky, MD (Stony Brook, NY) isSenior Vice President, Health Sciences and Dean of the School of Medicine, Stony Brook University.
Marshall A. Lichtman, MD (Rochester, NY) is Professor of Medicine and of Biochemistry and Biophysics, University of Rochester Medical Center.
Josef T. Prchal, MD (Salt Lake City, UT, and Prague, Czech Republic) is Professor of Medicine, Pathology, and Genetics, Hematology Division of the University of Utah, and Department of Pathophysiology, First Faculty of Medicine, Charles University in Prague.
Marcel M. Levi, MD, PhD (Amsterdam, The Netherlands) is Chairman of the Department of Medicine at the Academic Medical Center, University of Amsterdam.
Oliver W. Press, MD, PhD (Seattle, WA) is Member and Penny E. Petersen Endowed Chair of Lymphoma Research, Fred Hutchinson Cancer Research Center, Professor of Medicine at the University of Washington.
Linda J. Burns, MD (Minneapolis, MN) is Vice President and Medical Director, Health Services Research at National Marrow Donor Program/Be The Match.
Michael A. Caligiuri, MD (Columbus, OH) is Director, Comprehensive Cancer Center, CEO, James Cancer Hospital & Solove Research Institute, JL Marakas Nationwide Insurance Enterprise Foundation Chair of Cancer Research, The Ohio State University.