Hydrogen Bonding in Biological Structures

1. Auflage 1994
ISBN: 978-3-540-57903-8
Verlag: Springer

Buch, Englisch, 569 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 873 g

Hydrogen bonds are weak attractions, with a binding strength less than one-tenth that of a normal covalent bond. However, hydrogen bonds are of extraordinary importance; without them all wooden structures would collapse, cement would crumble, oceans would vaporize, and all living things would disintegrate into random dispersions of inert matter.
Hydrogen Bonding in Biological Structures is informative and eminently usable. It is, in a sense, a Rosetta stone that unlocks a wealth of information from the language of crystallography and makes it accessible to all scientists. (From a book review of Kenneth M. Harmon, Science 1992)

Zielgruppe

Research

Autoren/Hrsg.

Jeffrey, George A.

Saenger, Wolfram

Inhaltsverzeichnis

IA Basic Concepts.- 1 The Importance of Hydrogen Bonds.- 2 Definitions and Concepts.- 3 Experimental Studies of Hydrogen Bonding.- 4 Theoretical Calculations of Hydrogen-Bond Geometries.- 5 Effect of Hydrogen Bonding on Molecular Structure.- IB Hydrogen-Bond Geometry.- 6 The Importance of Small Molecule Structural Studies.- 7 Metrical Aspects of Two-Center Hydrogen Bonds.- 8 Metrical Aspects of Three- and Four-Center Hydrogen Bonds.- 9 Intramolecular Hydrogen Bonds.- 10 Weak Hydrogen-Bonding Interactions Formed by C-H Groups as Donors and Aromatic Rings as Acceptors.- 11 Halides and Halogen Atoms as Hydrogen-Bond Acceptors.- 12 Hydrogen-Bond Acceptor Geometries.- II Hydrogen Bonding in Small Biological Molecules.- 13 Hydrogen Bonding in Carbohydrates.- 14 Hydrogen Bonding in Amino Acids and Peptides: Predominance of Zwitterions.- 15 Purines and Pyrimidines.- 16 Base Pairing in the Purine and Pyrimidine Crystal Structures.- 17 Hydrogen Bonding in the Crystal Structures of the Nucleosides and Nucleotides.- III Hydrogen Bonding in Biological Macromolecules.- 18 O-H ··· O Hydrogen Bonding in Crystal Structures of Cyclic and Linear Oligoamyloses: Cyclodextrins, Maltotriose, and Maltohexaose.- 19 Hydrogen Bonding in Proteins.- 20 The Role of Hydrogen Bonding in the Structure and Function of the Nucleic Acids.- IV Hydrogen Bonding by the Water Molecule.- 21 Hydrogen-Bonding Patterns in Water, Ices, the Hydrate Inclusion Compounds, and the Hydrate Layer Structures.- 22 Hydrates of Small Biological Molecules: Carbohydrates, Amino Acids, Peptides, Purines, Pyrimidines, Nucleosides and Nucleotides.- 23 Hydration of Proteins.- 24 Hydration of Nucleic Acids.- 25 The Role of Three-Center Hydrogen Bonds in the Dynamics of Hydration and of Structure Transition.- References.-Refcodes.