James / Lazdunski / Pattus Bacteriocins, Microcins and Lantibiotics

Erscheinungsjahr 2013
ISBN: 978-3-642-76974-0
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 65, 519 Seiten, eBook

Reihe: NATO ASI Series

Zielgruppe

Research

Autoren/Hrsg.

James, Richard

Lazdunski, Claude

Pattus, Franc

Inhaltsverzeichnis

to the Microcin Session.- Escherichia coli genes regulating the production of microcins MCCB17 and MCCC7.- Uptake and mode of action of the peptide antibiotic microcin B17.- The structure and maturation pathway of microcin B17.- Bacteriocins of Gram-positive bacteria: an opinion regarding their nature, nomenclature and numbers.- Molecular properties of Lactobacillus bacteriocins.- Lactococcal bacteriocins: genetics and mode of action.- to the Lantibiotics session.- Lantibiotics : An overview and conformational studies on Gallidermin and Pep5.- Biosynthesis of the lantibiotic Pep5 and mode of action of type A lantibiotics.- Identification of genes involved in lantibiotic synthesis.- Pore forming bacteriocins.- In vivo properties of colicin A: channel activity and translocation.- Site-directed fluorescence spectroscopy as a tool to study the membrane insertion of colicin A.- Structure-function of the colicin E1 ion channel: voltage-driven translocation and gating of a tetra- (or hexa-) helix channel.- Voltage-dependent gating of colicin E1 channels in planar bilayers.- Immunity to colicins.- Immunity protein to pore forming colicins.- Specificity determinants for the interaction of colicin E9 with its immunity protein.- Structural studies on colicin E3 and its immunity protein.- Study of the import mechanisms of colicins through protein engineering and K+ efflux kinetics.- Import and export of colicin M.- TolA: structure, location and role in the uptake of colicins.- Domains of the Escherichia coli BtuB protein involved in outer membrane association and interaction with colicin translocation components.- A structure-function analysis of BtuB, the E.coli vitamin B12 outer membrane transport protein.- General introduction to the secretion of bacteriocins.- Functioning of the pCloDF13 encoded BRP.- Structure/function relationships in the signal sequence of the colicin A lysis protein.- The secretion of colicin V.- to the session on the evolution of bacteriocins.- Molecular evolution of E colicin plasmids with emphasis on the endonuclease types.- Immunity specificity and evolution of the nuclease-type E colicins.- Replicon evolution of ColE2-related plasmids.- Manuscripts of poster presentations.- Genetic determinants for microcin H47, an Escherichia coli chromosome-encoded antibiotic.- BLIS production in the genus Streptococcus.- A new Leuconostoc bacteriocin, Mesentericin Y105, bactericidal to Listeria monocytogenes.- Cloning and characterisation of a lysin gene from a Listeria bacteriophage.- Transformation of Enterococcus faecalis OGIX with the plasmid pMB2 encoding for the peptide antibiotic AS-48, by protoplast fusion and regeneration on calcium alginate.- NMR studies of lantibiotics: the three-dimensional structure of nisin in aqueous solution.- Localization and phenotypic expression of genes involved in the biosynthesis of the Lactococcus lactis subsp. lactis lantibiotic nisin.- Expression of nisin in Bacillus subtllis.- Tn5301, a Lactococcal transposon encoding genes for nisin biosynthesis.- Development of yeast inhibitory compounds for incorporation into silage inoculants.- The excC and excD genes of Escherichia coli K-12 encode the peptidoglycan-associated lipoprotein (PAL) and the TolQ protein, respectively.- Resistance and tolerance of bacteria to E colicins.- Construction and characterization of chimeric proteins between pyocins and colicin E3.- Colicins as anti-tumour drugs.- List of Participants.