The Kappa Opioid Receptor

1. Auflage 2022
ISBN: 978-3-030-89076-6
Verlag: Springer International Publishing

Buch, Englisch, Band 271, 577 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 1050 g

Reihe: Handbook of Experimental Pharmacology

This book covers the latest knowledge in structure, signaling, and biochemical pharmacology of KOR as well as preclinical research and clinical applications (including clinical phase studies and approved for human use) of KOR compounds. It is divided up into the three parts: Molecular aspects of KOR, Preclinical research on pharmacology of KOR agonists and antagonists in animals and KOR agonists and antagonists in clinical use and in past and present clinical trials.
The chapters "Biosensors monitor ligand-selective effects at kappa opioid receptors" and "The role of dynorphin and the kappa opioid receptor in schizophrenia and major depressive disorder: a translational approach" of this book are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Zielgruppe

Research

Autoren/Hrsg.

Inan, Saadet

Liu-Chen, Lee-Yuan

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

From the contents. Preface.-Part I: Molecular aspects of KOR.- Part II: Preclinical research on pharmacology of KOR agonists and antagonists in animals.- Part III: KOR agonists and antagonists in clinical use and in past and present clinical trials.