Early Detection of Biomarkers for Disease

Erscheinungsjahr 2017
ISBN: 978-1-84973-613-8
Verlag: ROYAL SOCIETY OF CHEMISTRY

Buch, Englisch, 500 Seiten, Format (B × H): 156 mm x 234 mm

Reihe: Detection Science

Many diseases can now be diagnosed at the sub-clinical level thanks to the identification of specific biomarkers, which often occur in concentrations close to the limit of detection of existing technologies.

While much of the literature examines specific biomarkers in the context of specific diseases, this book focusses on the detection of known biomarkers; demonstrating how the adaptation of existing techniques with the latest technological advances can identify the early onset of illnesses such as diabetes, leukaemia, Alzheimer’s, and cardiac disease.

The volume editors represent both academia and industry, and have drawn together contributions from researchers and clinicians. The first half of the book presents the latest technologies available, incorporating emerging fields such as genomics and metabolomics. Point-of-care systems for disease diagnosis are also discussed. Chapters in the second half of the book are dedicated to specific diseases.

With its unique approach to the topic, and input from all sectors involved, this book will prove invaluable to anyone wishing to see how modern detection science is assisting in the battle against disease, and how the tools available today can be improved for tomorrow.

Autoren/Hrsg.

Hoyle, Nicholas R.

Morgan, Richard

Weitere Mitwirkende

Reddy, Subrayal M

Arrigan, Damien

Thompson, Michael

Inhaltsverzeichnis

Part 1: Technology for early detection of biomarkers; Mass Spectrometry, Fluorescently Activated Cell Sorting; Metabolomics; Genomics; Point of Care Systems; Part 2: Early biomarkers of disease; Cardiac Diseases; Diabetes; Leukaemia; Cancer; Alzheimier's Disease

Über Autor(innen)

Reddy, Subrayal M
Dr. Sub Reddy (C.Chem. MRSC) obtained his first class degree in Chemistry from the University of Manchester. He received his Ph.D. in Membrane-based Electrochemical Biosensing from the same University (1996). His post-doctoral research interests have included the development of quartz crystal-based biosensors, operating in the liquid phase (University of Wales, Bangor; 1994-1997) and the development of application-specific odour sensors (UMIST, Manchester; 1997-1998).

Dr. Reddy was Senior Lecturer in Applied Analytical Chemistry at the University of Surrey and recently moved to the University of Central Lancashire as Senior Lecturer in Analytical Chemistry. Current research interests include the development of smart, permselective and biocompatible molecular imprinted polymers and membrane materials for the sensor/sample interface and the advancement of smart materials-based electrochemical, quartz crystal and optical sensors for medical, food and environmental applications. He is particularly interested in developing hydrogel-based molecularly imprinted polymers (HydroMIPs) for the determination of protein markers and other biomarkers and construction of biosensors.