Howard / Hood Commercial Plant-Produced Recombinant Protein Products

Case Studies
2014
ISBN: 978-3-662-43836-7
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 68, 281 Seiten, eBook

Reihe: Biotechnology in Agriculture and Forestry

Attention has recently turned to using plants as hosts for the production of commercially important proteins. The twelve case studies in this volume present successful strategies for using plants to produce industrial and pharmaceutical proteins and vaccine antigens. They examine in detail projects that have commercial potential or products that have already been commercialized, illustrating the advantages that plants offer over bacterial, fungal or animal cell-culture hosts. There are many indications that plant protein production marks the beginning of a new paradigm for the commercial production of proteins that, over the next decade, will expand dramatically.

Zielgruppe

Research

Autoren/Hrsg.

Howard, John A.

Hood, Elizabeth E.

Inhaltsverzeichnis

1 Introduction — Plant-produced protein productsElizabeth E. Hood and Paul ChristouPart I: Highly Purified Proteins2 Commercial Plant-Produced Recombinant AvidinElizabeth E. Hood and John A. Howard3 Molecular farming in plants – the long road to the marketRainer Fischer, Johannes F Buyel, Stefan Schillberg and Richard M Twyman4 TrypZean™: an animal-free alternative to bovine trypsinAparna Krishnan, Susan L. Woodard5 Production of Pharmaceutical Grade Recombinant Native Aprotinin and Non-Oxidized Aprotinin-Variants Under Greenhouse and Field Conditions Gregory P. Pogue, Fakhrieh Vojdani, Kenneth E. Palmer, Earl White, Hugh Haydon, Barry BratcherPart II: Vaccines6 Influenza virus-like particles produced in Nicotiana benthamiana protect against a lethal viral challenge in miceLouis-P Vézina, Brian J Ward, Marc-André D’Aoust, Manon Couture, Sonia Trépanier, Andrew Sheldon1, Nathalie Landry7 Plant-Produced Recombinant Transmission Blocking Vaccine Candidates to Combat MalariaStephen J. Streatfield, Natasha Kushnir, Vidadi Yusibov8 An oral vaccine for TGEV immunization of pigsRajan, V.9 Edible Rabies VaccinesElizabeth Loza-Rubio and Edith Rojas-Anaya10 Newcastle disease vaccinesMiguel A. Gómez Lim11 An oral vaccine for hepatitis B: challenges, setbacks, and breakthroughsCeline A. HaydenPart III: Industrial Proteins12 Commercial Plant-Produced Recombinant Cellulases for Biomass ConversionElizabeth E. Hood, Deborah V. Requesens13 Brazzein: A High Intensity Natural SweetenerGina Fake and John HowardPart IV: Future Directions14 The Future of Plant-Produced Pharmaceuticals and Industrial ProteinsJohn Howard, Elizabeth E. Hood