Fundamentals of Maldi-Tof-MS Analysis

Applications in Bio-Diagnosis, Tissue Engineering and Drug Delivery
2017. Auflage 2016
ISBN: 978-981-10-2355-2
Verlag: Springer Nature Singapore

Buch, Englisch, 68 Seiten, Format (B × H): 154 mm x 236 mm, Gewicht: 1358 g

Reihe: SpringerBriefs in Applied Sciences and Technology

This book presents the fundamentals and applications of Matrix Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-ToF-MS) technique. It highlights the basic principles, the history of invention as well as the mechanism of ionization and mass determination using this technique. It describes the fundamental principles and methods for MALDI spectra interpretation and determination of exact chemical structures from experimental data. This book guides the reader through the interpretation of MALDI data where complex macromolecular spectra are simplified in order to present the major principles behind data interpretation. In addition, each chapter describes how MALDI-ToF-MS analysis provides necessary understanding of the copolymer systems that have been designed for specialized biomedical applications.

Zielgruppe

Research

Autoren/Hrsg.

Hosseini, Samira

Martinez-Chapa, Sergio O

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Naturwissenschaften Biowissenschaften Zellbiologie
• Naturwissenschaften Physik Elektromagnetismus Mikroskopie, Spektroskopie
• Naturwissenschaften Chemie Analytische Chemie Magnetresonanz
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pharmazie
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Naturwissenschaften Chemie Analytische Chemie Massenspektrometrie, Spektroskopie, Spektrochemie

Inhaltsverzeichnis

Fundamentals of MALDI-ToF-MS analysis.- Application of MALDI-ToF-MS analysis in bio-diagnostic domain.- Application of MALDI-ToF-MS analysis in tissue engineering.- Application of MALDI-ToF-MS analysis in drug delivery.- References.- Summary.

Über Autor(innen)

Dr. Samira Hosseini obtained her BSc degree in Applied Physics, her MSc degree in Polymer Chemistry and her PhD degree in Biomedical Engineering. Currently, she is working as a Postdoctoral Researcher at School of Engineering and Sciences, Tecnológico de  Monterrey, Mexico. Her main areas of  research are surface engineering, interface science, bioanalytical systems and polymeric materials.

Sergio O. Martinez is a professor of Electrical and Computer Engineering at Tecnológico de Monterrey, Monterrey Campus; and Chair of the Sensors and Devices of the National School of Engineering and Sciences at the same Institute. He obtained his Ph.D. in Microelectronics from the National Polytechnic Institute of Grenoble, France in 2002. He  is a member of the Mexican Research National System since 2004 and the Mexican Academy of Sciences since 2010. His recent research activities, focused on Micro/Nanotechnolgies, include Microfabrication Processes for Particle Manipulation Devices, Electrokinetically-driven Microdevices for Manipulation of Suspended Particles in Fluidic Media, and Modeling and Design of SPR-based Biosensing Platforms. He has been Principal Investigator in projects funded by CONACYT, the Mexican Economy Ministry, and the Bureau of Science and Technology of Nuevo Leon. He has authored/coauthored 75 peer-reviewed publications, 7 book chapters and 2 granted patents.