Macrophages and Related Cells

1993
ISBN: 978-0-306-44362-6
Verlag: Springer US

Buch, Englisch, Band 5, 434 Seiten, HC runder Rücken kaschiert, Format (B × H): 183 mm x 260 mm, Gewicht: 1056 g

Reihe: Blood Cell Biochemistry

To produce a comprehensive overview of macrophages and related cell types in a short review volume is an impossible task. When I selected the topics to be included, some equally important areas were omitted by necessity, and for this I apologize. My choices have been somewhat eclectic, touching subjects of personal interest (such as osteoclast biology and macrophage electrophysiology) or of current fashion (apopto­ sis, antigen processing, cell adhesion molecules). The book has also had to encompass areas of a more general flavor to provide balance for the general reader (such as reviews of macrophage development, heterogeneity, and function, and of the surface molecules expressed by macrophages). I thank all the authors for their prompt sub­ missions; all have been of high quality, and my editorial tasks, thankfully, have been minimal. Michael A. Horton London, United Kingdom ix Contents Chapter J An Overview of Receptors of MPS Cells lain Fraser and Siam on Gordon 1. Introduction. 1 2. The Mononuclear Phagocyte System. 2 3. Diversity of Macrophage Plasma Membrane Receptors. 6 3. 1 A Structural Approach to Classification. 6. 8 3. 2 Multisubunit Receptors 3. 3 Soluble Receptors. 9 3. 4 Lectins and Lectin-Like Receptors. 12 4. Functions and Selected Examples. 14 4. 1 Growth, Differentiation, and Modulation. 14 4. 2 Cell-Cell and Cell-Matrix Interactions. 16 4. 3 Endocytosis and Scavenger Receptors. 16 4. 4 Secretory Responses and Biosynthesis of Effector Molecules. 17 5. Concluding Remarks. 17 6. References. 18.

Zielgruppe

Research

Autoren/Hrsg.

Horton, Michael A.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Biochemie (med.)
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Histologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Hämatologie, Transfusionsmedizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Innere Medizin

Inhaltsverzeichnis

1 An Overview of Receptors of MPS Cells.- 2 Heterogeneity of Mononuclear Phagocytes: An Interpretive Review.- 3 Origin of Macrophages.- 4 Complement and the Mononuclear Phagocyte System.- 5 Macrophages and Prostaglandins.- 6 Antigen Processing.- 7 Antigens of Osteoclasts: Phenotypic Definition of a Specialized Hemopoietic Cell Lineage.- 8 Electrophysiology of Osteoclasts and Macrophages.- 9 Complement Receptors.- 10 Fc? Receptors of Myeloid Cells.- 11 Matrix Receptors of Myeloid Cells.- 12 Leukocyte Integrins.- 13 Molecular Basis for Leukocyte Adhesion Molecule Deficiency.- 14 Carbohydrate-Recognition Proteins of Macrophages and Related Cells.- 15 Leukocyte Adhesion to Endothelium.- 16 Cell Recognition of Apoptotic Cells.