HIV I: Molecular Biology and Pathogenesis: Clinical Applications

2. Auflage 2007
ISBN: 978-0-12-373601-7
Verlag: William Andrew Publishing

Buch, Englisch, 638 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 1140 g

Although it is one of the most-widely studied viruses, many mysteries still remain about HIV. Covering the latest advances and challenges associated with clinical application of new antiviral drugs and vaccines, this revised edition is a companion to Murad: HIV-1: Molecular Biology and Pathogenesis, Second Edition. Leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus.

Zielgruppe

Graduate students, postdoctoral fellows, and senior researchers in virology and pharmacology, as well as clinicians and clinical fellows in infectious diseases

Autoren/Hrsg.

Weitere Mitwirkende

August, J. Thomas

Murad, Ferid

Jeang, Kuan-Teh

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Infektionskrankheiten
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin HIV, AIDS
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

HIV Therapeutics: Past, Present, and Future
HIV Drug Resistance and Viral Fitness
Inhibitors of HIV-1 Reverse Transcriptase

HIV-I Protease: Maturation, Enzyme Specificity, and Drug Resistance
HIV-I Integrase Inhibitors: Past, Present, and Future

Selection of HIV Replication Inhibitors: Chemistry and Biology
Maturation or assembly inhibitor compounds against HIV-1
HIV-I Gene Therapy: Promise for the Future

Assessment of HIV Vaccine Development: Past, Present, and Future

CTL immunity approaches for HIV-1 vaccines
humoral immunity approaches for HIV-1 vaccines.
HIV-I-Associated Central Nervous System Dysfunction
Molecular Mechanisms of Human Immunodeficiency Virus Type I Mother-Infact Transmission
Molecular Epidemiology of HIV-I: An Example of Asia

Simian Immunodeficiency Virus Infection of Monkeys as a Model System for the Study of AIDS Pathogenesis, Treatment and Prevention
Animal Models for AIDS Pathogenesis

SCID-hu mouse models for studying HIV-AIDS and for drug testing.

Über Autor(innen)

Murad, Ferid
Ferid Murad was born in Whiting, Indiana. Working concurrently on an M.D. and Ph.D. in Pharmacology, Dr. Murad graduated with both degrees from Case Western Reserve University, Cleveland, Ohio, in 1965. His many honors include the Alfred S. Maschke Award for Clinical Excellence from Case Western Reserve University in 1965. He has held several distinguished positions, including Acting Chairman in the Department of Medicine and Acting Division Chief, Division of Respiratory Medicine at Stanford University. He currently is CEO and President of Molecular Geriatrics Corporation in Lake Bluff, Illinois. Dr. Murad is married and has five children.