Marek's Disease

Softcover Nachdruck of the original 1. Auflage 2001
ISBN: 978-3-642-63217-4
Verlag: Springer

Buch, Englisch, Band 255, 296 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 476 g

Reihe: Current Topics in Microbiology and Immunology

Marek's disease virus (MDV) is a herpesvirus which causes a lymphoproliferative disorder of the domestic chicken worldwide. This serious economical problem caused by MDV was mostly solved by development of an effective vaccine against MDV. The development of live vaccines against the disease is remarkable as it has led to the first example of a commercially available vaccine against cancer as well as against diseases caused by herpesviruses.
This volume gives an overview on many aspects of MDV research and summarizes recent advances in the field. The topics include the history, biology,and molecular biology of MDV, pathogenesis, vaccinal immunity, immune response, genetic resistance and development of recombinant polyvalent vaccines. It is hoped that this volume will make an important contribution towards the control of infectious diseases.

Zielgruppe

Research

Autoren/Hrsg.

Hirai, K.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Naturwissenschaften Biowissenschaften Mikrobiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie

Inhaltsverzeichnis

List of Contents.- The History and Biology of Marek’s Disease Virus.- Pathogenesis of Marek’s Disease Virus Infection.- Protective Efficacy of Marek’s Disease Vaccines.- Immune Responses to Marek’s Disease Virus Infection.- Genetic Resistance to Marek’s Disease.- The Genomic Structure of Marek’s Disease Virus.- Protein-Coding Content of the Sequence of Marek’s Disease Virus Serotype 1.- A Complete Genomic DNA Sequence of Marek’s Disease Virus Type 2, Strain HPRS24.- Marek’s Disease Virus Latency.- Meq: An MDV-Specific bZIP Transactivator with Transforming Properties.- Polyvalent Recombinant Marek’s Disease Virus Vaccine Against Poultry Diseases.