Molecular Diagnostics

12 Tests That Changed Everything
Softcover Nachdruck of the original 1. Auflage 2014
ISBN: 978-1-4939-4265-7
Verlag: Springer

Buch, Englisch, 257 Seiten, Previously published in hardcover, Format (B × H): 178 mm x 254 mm, Gewicht: 5163 g

Reihe: Molecular and Translational Medicine

Molecular Diagnostics: 12 Tests That Changed Everything focuses on specific laboratory tests and emphasizes how the availability of these tests has altered how clinicians treat their patients. Presented as a standard outline, each chapter focuses on a specific molecular test and provides background on the test and its clinical applications. Continuing with some discussion on how the test is done, interpreted, and used clinically, each chapter then concludes with a discussion of how that test has changed the way medicine is practiced with respect to the disease or condition in question.

Authored by renowned experts in the field, Molecular Diagnostics: 12 Tests That Changed Everything is a valuable resource for pathologists, pathology residents, laboratory directors, development personnel, lab medicine fellows and those working in the broad area of oncology, infectious disease and genetics.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Highsmith, Jr.

Highsmith, Jr., W. Edward

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pathologie, Cytopathologie, Histopathologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie

Inhaltsverzeichnis

Oncology
 
1) Clinical FISH Testing for the Diagnosis of Solid Tumors
Benjamin R Kipp and Kevin C. Halling

2) Epidermal Growth Factor Receptor Testing in Lung Adenocarcinoma.
Neal I. Lindeman

3) The Human Epidermal Growth Factor Receptor 2 (HER2)
Laura J. Tafe and Gregory J. Tsongalis

4) Tamoxifen and Irinotecan Pharmacogenomics
John Logan Black III
   
 
Infectious Disease
 
5) Hepatitis C Virus Testing
Hassan M.E. Azzazy and  Karim M. Abdel Hady

6) Laboratory Testing for HIV Infection: Advances after 27 years
Joseph Nkeze; Niel Constantine; and Richard Y. Zhao

7) Detection of Herpes Simplex Virus in Cerebrospinal Fluid using Real-time PCR
Thomas F. Smith; Mark J. Espy; and Matthew J. Binnicker

8) Toward a Safer Blood Supply: The Impact of Molecular Testing
Niel T. Constantine; Patricia A. Wright; Ahmed Saleh; and Anna DeMarinis

 
Genetics
 
9) Chromosomal Microarrays
Umut Aypar; Swaroop Aradhya; Hutton Kearney; Christa Martin; Sarah South; and Eric Thorland

10) BRCA1 and BRCA2 Testing in Inherited Breast Cancer
Karla R. Bowles and Eric Rosenthal

11) Cystic Fibrosis: Carrier Testing, Newborn Screening, and Diagnostic Testing
W. Edward Highsmith, Jr.

12) Newborn Screening by Tandem Mass Spectrometry and Molecular Confirmation
Sean Hofer and Devin Oglesbee

Future Directions: The Test That will Change Everything - Again

13) Next Generation Clinical Diagnostics: The Sequence of Events
Nicole Hoppman; David I. Smith; Eric W. Klee; Matthew J. Ferber

Über Autor(innen)

W. Edward Highsmith, Jr., PhD
Mayo Clinic College of Medicine, Department of Laboratory Medicine and Pathology, Molecular Genetics Laboratory, Rochester, MN, USA