Grunwald Carbohydrate-Modifying Biocatalysts

Erscheinungsjahr 2012
ISBN: 978-981-4303-48-4
Verlag: Pan Stanford Publishing
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 846 Seiten

Carbohydrates have long been disregarded by the scientific community due to their complex structure and a lack of suitable experimental methods for structure determination. This book provides an overview of the structure, function, and application of carbohydrate-modifying biocatalysts. It explores glycoconjugates and carbohydrate-modifying enzymes and the key roles they play in biological processes such as recognition, signal transduction, and immune responses. It discusses research activities in glycoscience, including the development of several new pharmaceuticals to treat malaria, cancer, and other diseases.

Zielgruppe

Advanced undergraduate- and graduate-level students in chemistry, biology, biochemistry, and pharmacy; researchers (university, industry) in biology, chemistry, medicine, and pharmacy.

Autoren/Hrsg.

Grunwald, Peter

Fachgebiete

• Technische Wissenschaften Technik Allgemein Nanotechnologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pharmazie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie Biotechnologie: Mikrotechnologie, Nanobiotechnologie
• Naturwissenschaften Chemie Organische Chemie Biochemie
• Naturwissenschaften Chemie Physikalische Chemie Chemische Reaktionen, Katalyse
• Naturwissenschaften Biowissenschaften Kohlenhydrate
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)

Inhaltsverzeichnis

Basics in Carbohydrate Chemistry, H. Hühnerfuss
Glycoconjugates: An Overview, P. Grunwald
Oligosaccharides and Glycoconjugates in Recognition Processes, T. K. Lindhorst
Glycoside Hydrolases, M. Kitaoka
Disaccharide Phosphorylases: Mechanistic Diversity and Application in Glycosciences, C. Luley-Goedl and B. Nidetzky
Enzymatic and Chemo-Enzymatic Synthesis of Nucleotide Sugars: Novel Enzymes, Novel Substrates, Novel Products, and Novel Routs, L. Engels and L. Elling
Iteratively Acting Glycosyltransferases, M. Luzhetska and A. Bechthold
Bacterial Glycosyltransferases Involved in Molecular Mimicry of Mammalian Glycans, W. Wakarchuk
Sulfotransferases and Sulfatases: Sulfate Modification of Carbohydrates, Eli Chapman and Sarah R. Hanson
Glycosylation in Health and Disease, P. Grunwald
Sialic Acid Derivatives, Analogs and Mimetics as Biological Probes and Inhibitors of Sialic Acid Recognizing Proteins, J. Tiralongo and T. Haselhorst
Enzymes of the Carbohydrate Metabolism and Catabolism for Chemoenzymatic Syntheses of Complex Oligosaccharides, J. Thimm and J. Thiem
From Gene to Product — Tailor-Made Oligosaccharides and Polysaccharides by Enzyme and Substrate Engineering, J. Seibel
Synthesis and Modification of Carbohydrates via Metabolic Pathway Engineering in Microorganisms, X.-W. Liu, L. Li, H.-T. Gao, L.-J. Dang, and P. G. Wang
Metabolic Pathway Engineering for Hyaluronic Acid Production, E. Marcellin, Wendy Y. Chen, and L. K. Nielsen
Microbial Rhamnolipids, M. M. Müller, B. Hörmann, C. Syldatk, and R. Hausmann
Chitin-Converting Enzymes, K. Moß, S. Zibek, T. Hirth, and S. Rupp
Linear and Cyclic Oligosaccharides, H. Taniguchi
Fungal Degradation of Plant Oligo- and Polysaccharides, R. P. de Vries, M. Nadal, J. van der Brink, D. A. Vivas-Duarte, and H. Stålbrand
Bacterial Strategies for Plant Cell Wall Degradation and Their Genomic Information, Y. Tamaru and R. H. Doi
Design of Efficient Multi-Enzymatic Reactions for Cellulosic Biomass Processing, Anne S. Meyer