Multiple Myeloma

2011
ISBN: 978-3-540-85771-6
Verlag: Springer Berlin Heidelberg

Buch, Englisch, Band 183, 340 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 711 g

Reihe: Recent Results in Cancer Research

Multiple myeloma is currently still an incurable disease, but during the past decade knowledge of its molecular pathogenesis has increased rapidly. This has led to remarkable progress in both diagnosis and therapy, including in particular the approval of novel and first-in-class drugs such as thalidomide, bortezomib, and lenalidomide. This book, written by internationally acknowledged experts, covers a wide range of topics relating to multiple myeloma, including history, epidemiology, pathophysiology, clinical features, staging, and prognostic systems. The principal focus, however, is on therapy, with detailed information on the various promising treatment options which give hope that this cancer will be transformed into a chronic disease or even become curable. Individualized therapy and the variety of supportive treatment options, as described in this volume, will help in achieving this goal, as well as in reducing adverse events and improving quality of life.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Goldschmidt, Hartmut

Moehler, Thomas

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung

Inhaltsverzeichnis

History and epidemiology.- Pathophysiology: Molecular biology of plasma cell disorders.
Alterations in microenvironment.- Clinical Features: Imaging. Integrated innovative approach for diagnosis and staging.- Therapy: High-dose chemotherapy and ABSCT.- Allogeneic transplantation. Novel Drugs.- Immunotherapeutic approaches.- First-line treatment and maintenance.- Relapse.- Radiotherapy.- Kyphoplasty.- Supportive Therapy.- Appendix: Staging and prognosis systems.