Godfraind / Govoni / Paoletti Calcium Antagonists

Pharmacology and Clinical Research
1993
ISBN: 978-94-011-1725-8
Verlag: Springer Netherland
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 3, 381 Seiten, eBook

Reihe: Medical Science Symposia Series

Although the importance of calcium (Ca) in the maintenance of cardiac contractility was recognized as early as 1880, the critical role of the ion in the contractile process in skeletal, cardiac, and smooth muscle has only been established within the last three decades.
As the complexity of the pharmacological actions of the Ca channel inhibitors grows, there is a continued need to further clarify the inhibitors, both chemically and functionally.
This volume provides an update of the field based on the work presented at the 5th International Symposium on . It reviews the current state of the growing area of molecular biology of Ca channels. In the cardiovascular area, in addition to the well-established clinical uses of Ca channel inhibitors, exciting new work pointing to an application in atherosclerosis is described. The book also includes important uses of Ca antagonists in novel areas of interest such as the gastrointestinal tract, renal protection and multi-drug resistance.

Zielgruppe

Research

Autoren/Hrsg.

Godfraind, T.

Govoni, S.

Paoletti, Rodolfo

Vanhoutte, Paul M.

Inhaltsverzeichnis

I: Calcium Channels, the Molecular Approach. II: Cardiovascular Applications of Calcium Antagonists: from Pathophysiology to Therapy. A: Hypertension and Heart Failure. B: Atherosclerosis. III: Calcium Channels and Calcium Antagonists in Neurobiology and Nervous Disorders. IV: Novel Applications and Aspects of Calcium Antagonist Pharmacology. A: Gastrointestinal Tract. B: Renal Protection. C: Multidrug Resistance. Index.