Geddes / Lakowicz Glucose Sensing

2006
ISBN: 978-0-387-33015-0
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 11, 442 Seiten

Reihe: Topics in Fluorescence Spectroscopy

An essential reference for any laboratory working in the analytical fluorescence glucose sensing field. The increasing importance of these techniques is typified in one emerging area by developing non-invasive and continuous approaches for physiological glucose monitoring. This volume incorporates analytical fluorescence-based glucose sensing reviews, specialized enough to be attractive to professional researchers, yet appealing to a wider audience of scientists in related disciplines of fluorescence.

Autoren/Hrsg.

Geddes, Chris D.

Lakowicz, Joseph R.

Inhaltsverzeichnis

1;PREFACE;6
2;CONTRIBUTORS;7
3;CONTENTS;10
4;N-PHENYLBORONIC ACID DERIVATIVES OF ARENECARBOXIMDES AS SACCHARIDE PROBES WITH VIRTUAL SPACER DESIGN;20
4.1;1.1. INTRODUCTION;20
4.2;1.2. N-PHENYLBORONIC ACID ARENECARBOXIMIDES AS SACCHARIDE PROBES WITH VIRTUAL OR CO SPACER DESIGN;21
4.3;1.3. SUBSTITUENT EFFECTS ON MONOBORONIC ACID DERIVATIVES OF N-PHENYLl, 8-NAPHTHALENEDICARBOXIMIDES;22
4.4;1.4. POSITIONAL ISOMERS OF NAPHTHALENE DICARBOXIMIDES;32
4.5;1.5. CONCLUSION;35
4.6;1.6. SUMMARY AND OUTLOOK;36
4.7;1.7. ACKNOWLEDGMENTS;36
4.8;1.8. REFERENCES;36
5;GENESIS OF FLUOROPHORE FORMATION IN MACROCYCLE SOLUTIONS AND THE DETECTION OF GLUCOSE AND RELATED SUGARS;40
5.1;2.1. INTRODUCTION;40
5.2;2.2. THE DISCOVERY OF NEW FUNCTIONAL FLUOROPHORES;40
5.3;2.3. THE MECHANISM OF SUGARINDUCED SIGNAL TRANSDUCTION;47
5.4;2.4. A HIGHLY CONVENIENT NEW AUTOMATED HPLC POSTCOLUMN DETECTION METHOD FOR MONITORING GLUCOSE AND RELATED BIOMOLECULES;53
5.5;2.5. DETECTION OF GLUCOSE IN HUMAN BLOOD PLASMA AND PROGRESS TOWARDS CONCURRENT DETERMINATION OF GLUCOSE AND FRUCTOSE;57
5.6;2.6. CONCLUSION;61
5.7;2.7. ACKNOWLEDGMENTS;61
5.8;2.8. REFERENCES;61
6;TWO-COMPONENT OPTICAL SUGAR SENSING USING BORONIC ACID-SUBSTITUTED VIOLOGENS WITH ANIONIC FLUORESCENT DYES;65
6.1;3.1. INTRODUCTION;65
6.2;3.2. BACKGROUND AND ILLUSTRATION OF TWO-COMPONENT GLUCOSE SENSING - PYRANINE (HPTS) AND BORONIC ACID-FUNCTIONALIZED VIOLOGEN (o-BBV2+);68
6.3;3.3. VARIATIONS IN VIOLOGEN QUENCHER - BIPYRIDINIUM AND PHENANTHROLINIUM QUENCHERS;74
6.4;3.4. VARIATIONS IN FLUORESCENT REPORTER - SULFONAMIDE DERIVATIVES OF HPTS;89
6.5;3.5. IMMOBILIZATION OF THE SENSING COMPONENTS - A GLUCOSE SENSITIVE THIN FILM HYDROGEL;98
6.6;3.6. SUMMARY AND FUTURE DIRECTIONS;101
6.7;3.7. REFERENCES;102
7;IMPLANTABLE CONCANAVLIN A BASED SENSORS FOR INTERSTITIAL FLUID GLUCOSE SENSING IN DIABETICS;106
7.1;4.1. INTRODUCTION;106
7.2;4.2. CONCANAVALIN A AND DEXTRAN;109
7.3;4.3. FLUORESCENT BASED ASSAY;113
7.4;4.4. SENSING MODALITIES;117
7.5;4.5. SUMMARY;128
7.6;4.6. REFERENCES;128
8;FLUORESCENCE BIOSENSORS FOR CONTINUOUSLY MONITORING THE BLOOD GLUCOSE LEVEL OF DIABETIC PATIENTS;133
8.1;5.1. INTRODUCTION;133
8.2;5.2. GLUCOSE OXIDASE FROM ASPERGILLUS NIGER;135
8.3;5.3. THERMOSTABLE GLUCOSE DEHYDROGENASE FROM THERMOPLASMA ACIDOPHILUM;137
8.4;5.4. A FLUORESCENCE COMPETITIVE ASSAY BY USING THE STABLE GLUCOKINASE;139
8.5;5.5. CONCLUSIONS;142
8.6;5.6. ACKNOWLEDGMENT;143
8.7;5.7. REFERENCES;143
9;MICROCAPSULES AS "SMART TATTOO'' GLUCOSE SENSORS: ENGINEERING SYSTEMS WITH ENZYMES AND GLUCOSE-BINDING SENSING ELEMENTS;147
9.1;6.1. THE "SMART TATTOO" CONCEPT;147
9.2;6.2. LBL NANOFILMS AND POLYELECTROLYTE MICROCAPSULES;150
9.3;6.3. GLUCOSE SENSORS FROM NANOENGINEERED CAPSULES;152
9.4;6.4. ENZYME-BASED MICROCAPSULE SENSORS;158
9.5;6.5. GLUCOSEBINDING PROTEINS IN MICROCAPSULES;172
9.6;6.6. CONCLUSIONS;176
9.7;6.7. ACKNOWLEDGEMENT;177
9.8;6.8. REFERENCES;177
10;NON-INVASIVE MONITORING OF DIABETES: Specificity, compartmentalization, and calibration issues;180
10.1;7.1. INTRODUCTION;180
10.2;7.2. SPECIFICITY OF NI GLUCOSE MEASUREMENTS;182
10.3;7.3. COMPARTMENTALIZATION OF GLUCOSE VALUES;187
10.4;7.4. CALIBRATION MODELS AND PATIENT-SPECIFIC CALIBRATION;187
10.5;7.5. THERMO-OPTICAL RESPONSE OF HUMAN SKIN;188
10.6;7.6. ENHANCING SPECIFICITY BY AFFINITY CAPTURE AGENTS;205
10.7;7.7. CONCLUSIONS;210
10.8;7.8. REFERENCES;211
11;OPTICAL ENZYME-BASED GLUCOSE BIOSENSORS;215
11.1;8.1. ABSTRACT;215
11.2;8.2. INTRODUCTION;215
11.3;8.3. OPTICAL TRANSDUCTION USING COMMON OPTICAL TRANSDUCERS;217
11.4;8.4. IMMOBILIZATION OF GLUCOSE OXIDASE;221
11.5;8.5. CONSTRUCTION OF GLUCOSE BIOSENSOR;229
11.6;8.6. PERFORMANCE OF OPTICAL GLUCOSE BIOSENSOR;233
11.7;8.7. IMPLICATION OF THE DISSOLVED OXYGEN CONCENTRATION;237
11.8;8.8. ENHANCEMENT OF ENZYME STABILITY;238
11.9;8.9. ANALYTICAL FEATURE AND APPLICATION;240
11.10;8.10. CONCLUSION;242
11.11;8.11. ACKNOWLEDGMENT;243
11.12;8.12. REFERENCES;243
12;SACCHARIDE RECOGNITION BY BORONIC ACID FLUOROPHORE/CYCLODEXTRIN COMPLEXES IN WATER;251
12.1;9.1. ADVANCES IN SYNTHETIC RECEPTORS FOR SACCHARIDES;251
12.2;9.2. SACCHARIDE RECOGNITION BY BORONIC ACID FLUOROPHORE ß-CYCLODEXTRIN COMPLEXES;256
12.3;9.3. FUTURE PERSPECTIVE OF SUPRAMOLECULAR CYCLODEXTRIN COMPLEX SENSORS;268
12.4;9.4. ACKNOWLEDGEMENT;270
12.5;9.5. REFERENCES;271
13;PLASMONIC GLUCOSE SENSING;273
13.1;10.1. INTRODUCTION;273
13.2;10.2. OPTICAL PROPERTIES OF GOLD NANOPARTICLES;274
13.3;10.3. PREPARATION OF LIGAND FUNCTIONALIZED GOLD NANOPARTICLES FOR GLUCOSE SENSING AND OTHER APPLICATIONS;275
13.4;10.4. PLASMONIC GLUCOSE SENSING;278
13.5;10.5. CONCLUSIONS AND FUTURE DIRECTIONS;294
13.6;10.6. ACKNOWLEDGMENTS;294
13.7;10.7. REFERENCES;294
14;OPTICALLY-BASED AFFINITY BIOSENSORS FOR GLUCOSE;297
14.1;11.1. INTRODUCTION;297
14.2;11.2. DEVELOPMENT OF OPTICALLY BASED BIOSENSORS;299
14.3;11.3. COMPETITIVE OPTICAL AFFINITY GLUCOSE BIOSENSORS;303
14.4;11.4. DYNAMICS OF AFFINITY BIOSENSORS;312
14.5;11.5. RECENT DEVELOPMENTS IN AFFINITY BASED GLUCOSE BIOSENSOR SYSTEMS;313
14.6;11.6. INTEGRAL BIOSENSOR PROTEINS;318
14.7;11.7. ENHANCEMENTS OF OPTICAL GLUCOSE BIONSENSORS BASED ON AFFINITY PRINCIPLES;319
14.8;11.8. CONCLUSION;321
14.9;11.9. REFERENCES;321
15;RECENT CHEMILUMINESCENCE APPLICATIOINS FOR GLUCOSE SENSING;325
15.1;12.1. INTRODUCTION;325
15.2;12.2. CHEMILUMINESCENCE FOR THE DETERMINATION OF GLUCOSE;326
15.3;12.3. CHEMILUMINOGENIC BIOSENSOR;327
15.4;12.4. CAPILLARY ELECTROPHORESIS FOR GLUCOSE DETERMINATION;331
15.5;12.5. GLUCOSE SENSING: RECENT APPROACHES FOR CLINICAL USE IN DIABETES CARE;333
15.6;12.6. ACKNOWLEDGEMENT;335
15.7;12.7. REFERENCES;335
16;THE GLUCOSE BINDING PROTEIN AS GLUCOSE SENSOR;337
16.1;13.1. INTRODUCTION;337
16.2;13.2. PROTEIN ENGINEERING;338
16.3;13.3. POLARITY SENSITIVE PROBES;340
16.4;13.4. STRATEGIES FOR LOW-COST GLUCOSE SENSING;340
16.5;13.5. APPLICATION OF THE GBP-BASED BIOSENSOR IN CELL CULTURE;343
16.6;13.6. VALIDATION;344
16.7;13.7. REFERENCES;345
17;FLUORESCENT TICT SENSORS FOR SACCHARIDES;346
17.1;14.1. INTRODUCTION;346
17.2;14.2. RESULTS AND DISCUSSION;346
17.3;14.3. CONCLUSIONS;358
17.4;14.4. EXPERIMENTAL;358
17.5;14.5. ACKNOWLEDGMENTS;363
17.6;14.6. REFERENCES;363
18;GLUCOSE SENSING AND GLUCOSE DETERMINATION USING FLUORESCENT PROBES AND MOLECULAR RECEPTORS;364
18.1;15.1. ABSTRACT;364
18.2;15.2. INTRODUCTION;365
18.3;15.3. DETERMINATION OF GLUCOSE VIA GOx AND FLUORESCENT MOLECULAR PROBES;367
18.4;15.4. CONTINOUS SENSING OF GLUCOSE USING FLUORESCENT SENSOR MEMBRANES;371
18.5;15.5. SENSING GLUCOSE VIA METAL-LIGAND COMPLEXES WITH A BORONIC ACID AS THE RECOGNITION SITE;377
18.6;15.6. SENSING GLUCOSE VIA THIN FILMS OF ORGANIC CONDUCTING POLYMERS (OCPs);378
18.7;15.7. SENSING GLUCOSE VIA OXYGEN-SENSITIVE NANOPARTICLES;380
18.8;15.8. SENSING GLUCOSE VIA THE INITRINSIC FLUORESCENCE OF GLUCOSE OXIDASE;380
18.9;15.9. IMAGING TECHNIQUES FOR GLUCOSE AND GLUCOSE OXIDASE;381
18.10;15.10. REFERENCES;386
19;BORONIC ACID-BASED FLUORESCENCE SENSORS FOR GLUCOSE MONITORING;389
19.1;16.1. INTRODUCTION;389
19.2;16.2. FACTORS THAT AFFECT THE BINDING BETWEEN BORONIC ACIDS AND DIOLS;390
19.3;16.3. VARIOUS TYPES OF BORONIC ACID-BASED FLUORESCENT REPORTER COMPOUNDS AVAILABLE;392
19.4;16.4. APPROACHES AVAILABLE FOR THE CONSTRUCTION OF THE APPROPRIATE 3-DIMENSIONAL SCAFFOLD FOR THE SELECTIVE RECOGNITION OF THE TARGET SUGAR;404
19.5;16.5. CONCLUSION;406
19.6;16.6. ACKNOWLEDGEMENT;406
19.7;16.7. REFERENCES;406
20;DEVELOPMENT OF SMART CONTACT LENSES FOR OPHTHALMIC GLUCOSE MONITORING;410
20.1;17.1. INTRODUCTION;410
20.2;17.2. GLUCOSE SENSING USING BORONICACID PROBES IN SOLUTION;413
20.3;17.3. LENS FEASIBITY STUDY;419
20.4;17.4. RATIONALE DESIGN OF NEW GLUCOSE SENSING PROBES;424
20.5;17.5. GLUCOSE SENSING PROBES BASED ON THE QUINOLINIUM MOIETY;425
20.6;17.6. PROBE LEACHING, INTERFERENTS AND SHELF LIFE;433
20.7;17.7. FUTURE DEVELOPMENTS BASED ON THIS TECHNOLOGY;435
20.8;17.8. CONCLUDING REMARKS;437
20.9;17.9. ACKNOWLEDGEMENTS;438
20.10;17.10. REFERENCES;438
21;INDEX;449