Hormone Therapy in Breast and Prostate Cancer

Softcover Nachdruck of the original 1. Auflage 2002
ISBN: 978-1-60761-471-5
Verlag: Humana Press

Buch, Englisch, 420 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 1350 g

Reihe: Cancer Drug Discovery and Development

In Hormone Therapy in Breast and Prostate Cancer, many of today's leading researchers and clinicians describe the principles underlying targeted hormonal treatments, assess the actions of new and established agents, and illustrate the new applications of hormonal chemoprevention for breast cancer. Topics range from preclinical and clinical antiestrogens to the inhibition of estrogen synthesis and the effects of androgen withdrawal. A wide variety of proven and new agents are discussed-antiestrogens, including aromatase inhibitors (anastrozole, letrozole, and others), SERMs (tamoxifen, raloxifene, and others), and such antiandrogenic strategies as goserelin and bicalutamide.

Zielgruppe

Research

Autoren/Hrsg.

Furr, B. J. A.

V. CRAIG, JORDAN

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Endokrinologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Physiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Bildgebende Verfahren, Nuklearmedizin, Strahlentherapie Nuklearmedizin, PET, Radiotherapie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Urologie, Andrologie, Venerologie

Inhaltsverzeichnis

An Introduction to the Regulation of Sex Steroids for the Treatment of Cancer.- An Introduction to the Regulation of Sex Steroids for the Treatment of Cancer.- Preclinical Antiestrogens.- Antiestrogens and the Cell Cycle.- Drug Resistance to Antiestrogens.- Mechanisms of Liver Carcinogenesis by Antiestrogens.- The Effects of Triphenylethylene Antiestrogens on Parameters of Multistage Hepatocarcinogenesis in the Rat.- Preclinical Studies of Raloxifene and Related Compounds.- Pure Antiestrogens.- Antiestrogens: Clinical.- Tamoxifen for the Treatment of Breast Cancer.- Clinical Utility of New Antiestrogens.- Breast-Cancer Prevention with Antiestrogens.- Inhibition of Estrogen Synthesis.- Aromatase Inhibitors.- Clinical Utility of Aromatase Inhibitors.- LH-RH Agonists for the Treatment of Breast Cancer.- Androgens and Androgen Withdrawal.- Molecular Action of Androgens.- Steroidal Antiandrogens.- Nonsteroidal Antiandrogens.- LH-RH Agonist Role in Prostate Cancer Management.- Perspective on Progress.- Recent Progress in Breast Cancer Research.