Furr Aromatase Inhibitors
2., revidierte Auflage 2008
ISBN: 978-3-7643-8693-1
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark
E-Book, Englisch, 189 Seiten, eBook
Reihe: Milestones in Drug Therapy
ISBN: 978-3-7643-8693-1
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark
This book provides the first comprehensive overview on the different aromatase inhibitors. Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not very potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency.
Zielgruppe
Research
Autoren/Hrsg.
Weitere Infos & Material
Background and development of aromatase inhibitors.- Aromatase inhibitors and models for breast cancer.- Clinical pharmacology of aromatase inhibitors.- Clinical studies with exemestane.- Clinical studies with letrozole.- Clinical studies with anastrozole.- The third-generation aromatase inhibitors: a clinical overview.- Lessons from the ArKO mouse.- Possible additional therapeutic uses of aromatase inhibitors
