E-Book, Englisch, 436 Seiten
Friedman / Bendinelli / Specter In vivo Models of HIV Disease and Control
1. Auflage 2007
ISBN: 978-0-387-25741-9
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark
E-Book, Englisch, 436 Seiten
Reihe: Infectious Agents and Pathogenesis
ISBN: 978-0-387-25741-9
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark
An AIDS vaccine is still elusive and HIV treatment continues to develop multidrug resistance at alarming rates. Because of the similarities between HIV and immune deficiency infections in a variety of animals, it is only natural that scientists use these animals as models to study pathogenesis, treatment, vaccine development and many other aspects of HIV. Part of the series Infectious Agents and Pathogenesis, this volume reviews the immune deficiency virus in a variety of hosts. Pathogenesis, vaccine and drug development, epidemiology, and the natural history of the monkey, mouse, cat, cow, horse, and other animal viruses are detailed and compared to HIV. Also included are chapters on the history and future of animal models, as well as a chapter on ethical and safety considerations in using animal models for AIDS studies.
Autoren/Hrsg.
Weitere Infos & Material
1;Contributors;6
2;Preface to the Series;9
3;Preface;10
4;Contents;12
5;Historical Perspective;18
6;Animal Model Systems of HIV- Diseases;36
7;Chemokines and Their Receptors and the Neuropathogenesis of HIV- 1 Infection;61
8;SCID Mice Transplanted With Human Cells as Small Animal Models in AIDS Research;97
9;SIV as a Model for AIDS Pathogenesis Studies;116
10;SIV Infection of Macaques as a Model for AIDS Drug Studies;135
11;FIV as a Model for HIV: An Overview;162
12;FIV as a Model for AIDS Pathogenesis Studies;251
13;Drugs of Abuse, AIDS, and the FIV Model;286
14;FIV as a Model for AIDS Vaccine Studies;303
15;FIV as a Model for HIV Treatment;343
16;Equine Infectious Anemia Virus as a Model for Lentiviral Pathogenesis;375
17;Studies of the Structure of Caprine Arthritis- Encephalitis Virus Surface Envelope Glycoprotein;401
18;Ethical Issues in the Use of Animal Models of Infection and Some Practical Re . nements;414
19;Future Perspectives;434
20;Index;438
