Fong Emerging Issues and Controversies in Infectious Disease

1. Auflage 2009
ISBN: 978-0-387-84841-9
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 390 Seiten

Reihe: Emerging Infectious Diseases of the 21st Century

In this edition of the Emerging Infectious Diseases of the 21st Century Series, the editor reviews the research, diagnosis, and treatment of some common infections facing researchers, clinicians and family physicians such as sinusitis, otitis media and pertussis in adults. Recent studies and surveys have shown that these conditions are often over diagnosed and treated unnecessarily with antibiotics. The approach and guidelines for diagnosis and management are reviewed in this volume. Other more complicated but less common conditions challenging internists, clinical infectious disease consultants and other specialists are also reviewed (i.e. meningitis, ventilator associated pneumonia, sepsis, hepatitis C, B, etc.).

Autoren/Hrsg.

Fong, I. W.

Inhaltsverzeichnis

1;Preface;7
2;Contents;8
3;Acknowledgment;14
4;Bacterial and Fungal Infections;15
4.1;Issues in Central Nervous System Infections;16
4.1.1;1.1 Bacterial Meningitis ;16
4.1.2;1.2 Adjunctive Therapy in Tuberculous Meningitis ;28
4.1.3;1.3 Adjunctive Therapy in Fungal Meningitis ;31
4.1.4;1.4 Future Directions;33
4.1.5;References;35
4.2;Emerging Issues in Head and Neck Infections;40
4.2.1;2.1 Current Issues in Sinusitis ;40
4.2.2;References;56
5;Emerging Trends in Pulmonary Infection;60
5.1;Current Issues in Ventilator-Associated Pneumonia;61
5.1.1;3.1 Background;61
5.1.2;3.2 Issues in the Diagnosis of VAP;61
5.1.3;3.3 Microbial Etiology of VAP;68
5.1.4;3.4 Issues in Treatment of VAP;69
5.1.5;3.5 Prevention of VAP;72
5.1.6;3.6 Future Directions;78
5.1.7;References;79
5.2;Emerging Issues in Pulmonary Infections of Cystic Fibrosis;87
5.2.1;4.1 Introduction;87
5.2.2;4.2 Pathobiology of Cystic Fibrosis;87
5.2.3;4.3 Microbiology;90
5.2.4;4.4 Management of Infections in CF;95
5.2.5;4.5 Prevention of Infections in CF;102
5.2.6;4.6 Adjunctive Therapy for Pulmonary Exacerbation;102
5.2.7;4.7 Future Directions;104
5.2.8;References;106
5.3;Re-Emergence of Childhood Respiratory Infections in Adults ( RSV & Pertussis);114
5.3.1;A: Respiratory Syncytial Virus infection in Adults;114
5.3.1.1;5.1 Introduction;114
5.3.1.2;5.2 Microbiology and Pathogenesis;114
5.3.1.3;References for A;120
5.3.2;B: Pertussis in Adults;124
5.3.2.1;5.3 Introduction;124
5.3.2.2;References;132
6;New Concepts and Trends;135
6.1;New Concepts and Emerging Issues in Sepsis;136
6.1.1;6.1 Introduction;136
6.1.2;6.2 Definitions;137
6.1.3;6.3 Immune Response;137
6.1.4;6.4 Pathogenesis;139
6.1.5;6.5 Management in Sepsis;150
6.1.6;6.6 Early Goal-Directed Therapy;150
6.1.7;6.7 Antimicrobial Therapy in Severe Sepsis;151
6.1.8;6.8 Activated Protein C;153
6.1.9;6.9 Corticosteroids in Severe Sepsis;154
6.1.10;6.10 Intensive Insulin Therapy;155
6.1.11;6.11 Vasopressin and Vasopressors;156
6.1.12;6.12 Blood Products in Sepsis;156
6.1.13;6.13 Ventilation and Other Adjunctive Therapy;157
6.1.14;6.14 Immunotherapies for Sepsis;158
6.1.15;6.15 Genetics and Sepsis;159
6.1.16;6.16 Future Directions;160
6.1.17;6.17 Conclusion;163
6.1.18;References;163
6.2;Febrile Neutropenia: Management Issues;173
6.2.1;7.1 Introduction;173
6.2.2;7.2 Pathogenesis;174
6.2.3;7.3 Febrile Neutropenia Definition;175
6.2.4;7.4 Microbiology and Etiology;176
6.2.5;7.5 Duration of Therapy;182
6.2.6;7.6 Empiric Antifungal Therapy;183
6.2.7;7.7 Prevention;185
6.2.8;7.8 Future Directions;188
6.2.9;References;189
6.3;Emerging Issues and Trends in Clostridium difficile Colitis;197
6.3.1;8.1 Introduction;197
6.3.2;8.2 Microbiology;197
6.3.3;8.3 Pathogenesis;198
6.3.4;8.4 Clinical Aspects;202
6.3.5;8.5 Diagnosis;207
6.3.6;8.6 Management;208
6.3.7;References;222
6.4;Probiotics in Infectious Diseases;234
6.4.1;9.1 Introduction;234
6.4.2;9.2 Background;235
6.4.3;9.3 Mechanisms of Action;236
6.4.4;9.4 Clinical Application of Probiotics;242
6.4.5;9.5 Probiotics as Food Additives;256
6.4.6;9.6 Adverse Effects of Probiotics;257
6.4.7;9.7 Conclusion and Future Directions;257
6.4.8;References;258
6.5;Device-Related Infections;268
6.5.1;10.1 Introduction;268
6.5.2;10.2 Pathogenesis of Device-Related Infections;270
6.5.3;10.3 Specific Device-Related Infections ;274
6.5.4;10.4 Cardiovascular Device Infectious ;284
6.5.5;10.5 Vascular Grafts;292
6.5.6;10.6 Future Directions;294
6.5.7;References;295
6.6;Current Concepts of Orthopedic Implants and Prosthetic Joint Infections;305
6.6.1;11.1 Introduction;305
6.6.2;11.2 Microbiological Aspects;305
6.6.3;11.3 Diagnosis;308
6.6.4;11.4 Clinical Presentation;310
6.6.5;11.5 Management;311
6.6.6;11.6 Prevention of Orthopedic Device Infections;322
6.6.7;11.7 Future Directions;324
6.6.8;11.8 Conclusion;325
6.6.9;References;325
6.7;Combination Antimicrobial Therapies;333
6.7.1;12.1 Introduction;333
6.7.2;12.2 Bacterial Infections ;334
6.7.3;12.3 Fungal Infections and Combination Therapy;344
6.7.4;12.4 Viral Infections;353
6.7.5;12.5 Parasitic Infections;361
6.7.6;12.6 Conclusion;368
6.7.7;12.7 Future Directions;370
6.7.8;References;370
7;Index;384