ß-barrel Channel Proteins as Tools in Nanotechnology

Biology, Basic Science and Advanced Applications
2014
ISBN: 978-94-007-7428-5
Verlag: Springer Netherlands

Buch, Englisch, Band 794, 168 Seiten, Format (B × H): 183 mm x 260 mm, Gewicht: 5309 g

Reihe: Advances in Experimental Medicine and Biology

ß-barrel outer membrane channel proteins (OMP) are useful as robust and flexible models or components in nanotechnology. Over the last decade biotechnological techniques allowed to expand the natural characteristics of OMPs by modifying their geometry and properties. The present book is oriented towards a broad group of readers including graduate students and advanced researchers. It gives a general introduction to the field of OMP based nano-component development as well as the state of the art of the involved research. On the example of the E. coli FhuA the transformation of an OMP into a tailored nano-channel will be outlined. An exhaustive description of the scientific strategy, including protein selection, analytical methods and “in-silico” tools to support the planning of protein modifications for a targeted application, consideration on the production of a custom made OMP, and an overview on technological applications including membrane/polymersome technology, will be provided.

Zielgruppe

Research

Autoren/Hrsg.

Fioroni, Marco

Rodriguez-Ropero, Francisco

Dworeck, Tamara

Fachgebiete

• Naturwissenschaften Biowissenschaften Proteinforschung
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie Medizinische Biotechnologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie Biotechnologie: Mikrotechnologie, Nanobiotechnologie

Inhaltsverzeichnis

Preface.- Introduction.- Biology.- Biophysical Characterization.- Theoretical Considerations and Computational Tools.- Biotechnology.- Technological Applications.- Final Considerations.
Index.