E-Book, Englisch, 414 Seiten
Felton Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms, Fourth Edition
4. Auflage 2016
ISBN: 978-1-4987-3209-3
Verlag: CRC Press
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)
E-Book, Englisch, 414 Seiten
Reihe: Drugs and the Pharmaceutical Sciences
ISBN: 978-1-4987-3209-3
Verlag: CRC Press
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)
This book presents a comprehensive overview of aqueous polymeric coatings of pharmaceutical drug products. Thoroughly updated and expanded, this new fourth edition provides the latest information on dosage, forms, film defects, and polymer characterization. A new chapter has been added on substrate considerations when developing an aqueous film coated solid oral dosage form. Revised chapters include new material on coating process, equipment advances, troubleshooting, insoluble additives such as talc, chemistry, and application properties.
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
Aqueous-based polymeric coating. Pseudolatex dispersions for controlled drug delivery. Processing and equipment considerations for aqueous-based coatings. Mechanical properties of polymeric films prepared from aqueous dispersions. Defects in aqueous film coated solid oral dosage form. Adhesion of polymeric films. Influence of insoluble additives on the properties of polymeric coating systems. Process and formulation factors affecting drug release from pellets coated with ethylcellulose pseudolatex Aquacoat. Chemistry and application properties of polymethacrylate systems. Application of HPMC and HPMCAS to aqueous film coating of pharmaceutical dosage forms. The applications of formulated systems for aqueous film coating of pharmaceutical solid oral dosage forms. *Substrate considerations when developing an aqueous film coated solid oral dosage form. Polymer interactions with drugs and excipients. Physical aging of polymers and it effect on the stability of solid oral dosage forms.
