Zebrafish Models of Neurodegenerative Disorders

1. Auflage 2025
ISBN: 978-1-032-66046-2
Verlag: Taylor & Francis Ltd

Buch, Englisch, 380 Seiten, Format (B × H): 210 mm x 280 mm, Gewicht: 860 g

Reihe: Neuroscience of Neurodegenerative Disease

Advancing our understanding of neurodegenerative diseases demands innovative tools and approaches. Zebrafish Models in Neurodegenerative Disorders offers a comprehensive examination of zebrafish as a translational model for studying the molecular and cellular mechanisms of diseases such as Alzheimer’s, Parkinson’s, and Huntington’s diseases. Beginning with the first section informing about the basic molecular mechanisms of neurodegenerative disorders, biomarkers, and therapeutic approaches, the book continues with the detailed exploration of zebrafish physiology, genetics, and behavioural phenotypes as they pertain to neurodegenerative pathologies; insight into cutting-edge technologies, including CRISPR/Cas9 genome editing; and in-depth analysis of zebrafish models, highlighting their strengths in modelling disease progression and therapeutic testing.

Zielgruppe

Academic and Professional Reference

Autoren/Hrsg.

Emekli-Alturfan, Ebru

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Medizinische Diagnose und Diagnostik
• Naturwissenschaften Biowissenschaften Tierkunde / Zoologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Geriatrie, Gerontologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik
• Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
• Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft

Über Autor(innen)

Dr. Ebru Emekli-Alturfan received her PhD in biochemistry from the University of Marmara in 2006 and was appointed as a professor in the Faculty of Dentistry at Marmara University, specifically within the Department of Basic Medical Sciences in 2016. Ebru Emekli-Alturfan leads a research group using Zebrafish as a model organism to investigate molecular mechanisms of neurodegeneration. Their research encompasses neurodegeneration, neurodevelopment, and its molecular regulation in vertebrate development. They use zebrafish as a main model system. To investigate the genetic foundation of human diseases, they work together with colleagues both within the Medical and Dental School and internationally to develop and implement in vivo models. Besides leading a research group, Ebru Emekli-Alturfan teaches medical biochemistry courses at Marmara University's Faculty of Dentistry and Institute of Health Sciences.