Buch, Englisch, 516 Seiten, Format (B × H): 182 mm x 261 mm, Gewicht: 1177 g
Buch, Englisch, 516 Seiten, Format (B × H): 182 mm x 261 mm, Gewicht: 1177 g
Reihe: Cancer Drug Discovery and Development
ISBN: 978-1-58829-564-4
Verlag: Humana Press
Expert bench and clinical scientists join forces to concurrently review both the state-of-the-art in tumor immunology and its clinical translation into promising practical treatments. The authors explain in each chapter the scientific basis behind such therapeutic agents as monoclonal antibodies, cytokines, vaccines, and T-cells, and illustrate their clinical manipulation to combat cancer. Additional chapters address statistical analysis-both of clinical trials and assay evaluations-methods for the discovery of antigens, adoptive T cell therapy, and adaptive and innate immunity. The challenges in clinical trial design, the need for biomarkers of response-such as novel imaging techniques and immunologic monitoring-and the new advances and directions in cancer immunotherapy are also fully examined.
Zielgruppe
Professional/practitioner
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Labormedizin
Weitere Infos & Material
Discovery of Target Molecules for Cancer Immunotherapy by Genetic and Bioinformatic Approaches.- Current Strategies for the Identification of Immunogenic Epitopes of Tumor Antigens.- Current and Future Role of Natural-Killer Cells in Cancer Immunotherapy.- The Role of Immune Monitoring in Evaluating Cancer Immunotherapy.- Statistical Analysis of Immune Response Assays in Cancer Immunotherapy Trials.- DNA Vaccines for Cancer Immunotherapy.- Dendritic Cells.- Different Approaches to Dendritic Cell-Based Cancer Immunotherapy.- Anti-Idiotype Antibody Vaccines for the Immunotherapy of Cancer.- Autologous Tumor-Derived Heat Shock Protein Vaccine as a New Paradigm for Individualized Cancer Therapeutics.- Tumor-Reactive T-Cells for Adoptive Immunotherapy.- T-Cell Adoptive Immunotherapy of Cancer.- Retroviral-Mediated Gene Transfer for Engineering Tumor-Reactive T-Cells.- Harnessing the Potential of Graft-vs-Tumor.- Tumor-Induced Immune Suppression and Immune Escape.- The Tumor Microenvironment.- Manipulation of Lymphocyte Homeostasis for Enhancing Antitumor Immunity.- Fast-Lane Evolution in the Tumor Microenvironment.- Manipulating Immunological Checkpoints to Maximize Antitumor Immunity.- Interleukin-2 as Cancer Therapy.- Biological and Clinical Properties of the Type 1 Interferons.- Promising ?-Chain Cytokines for Cancer Immunotherapy.- The Therapeutic Use of Natural-Killer Cells in Hematological Malignancies.- Antibody Therapy for Solid Tumors.- Antibody Therapy for Non-Hodgkin’s Lymphoma.- Approaches to In Vivo Imaging of Cancer Immunotherapy.- Design Issues for Early-Stage Clinical Trials for Cancer Vaccines.- Monoclonal Antibody Therapy of Cancer.
