Copani / Nicoletti Cell-Cycle Mechanisms and Neuronal Cell Death

1. Auflage 2007
ISBN: 978-0-387-29390-5
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 110 Seiten

Reihe: Neuroscience Intelligence Unit

Cell-Cycle Mechanisms and Neuronal Cell Death examines the role of cell cycle activation in the molecular mechanisms leading to neuronal degeneration. Leading Authors discuss this topic in relation to the major neurological disorders, including Alzheimer's disease, stroke and epilepsy. This book serves to gain new insights into the molecular determinants of neuronal death and to establish new targets for therapeutic intervention.

Autoren/Hrsg.

Copani, Agata

Nicoletti, Ferdinando

Inhaltsverzeichnis

1;CONTENTS;4
2;EDITOR;6
3;CONTRIBUTORS;6
4;PREFACE;8
5;CHAPTER 1 Cell Cycle Activation in Neurons: The Final Exit of Brain-Morpho-Dysregulation;9
6;CHAPTER 2 Paved with Good Intentions: The Link between Cell Cycle and Cell Death in the MammaUan Central Nervous System;30
7;CHAPTER 3 The Role of Presenilins in the Cell Cycle and Apoptosis;38
8;CHAPTER 4 Cell Cycle Activation and Cell Death in the Nervous System;50
9;CHAPTER 5 Cell Cycle and Chromosome Segregation Defects in Alzheimer's Disease;63
10;CHAPTER 6 Alzheimer Disease: A New Beginning or a Final Exit?;87
11;CHAPTER 7 From Cell Cycle Activation to the Inhibition of the Wnt Pathway: A Hypothesis of How Neurons Die in Response to p-Amyloid;102
12;Index;109