Conn Computers and Computations in the Neurosciences

1. Auflage 2013
ISBN: 978-1-4832-5951-2
Verlag: Elsevier Science & Techn.
Format: EPUB
Kopierschutz: 6 - ePub Watermark

E-Book, Englisch, 602 Seiten

Methods in Neurosciences, Volume 10: Computers and Computations in the Neurosciences discusses the use of computers in the neurosciences. The book deals with data collection, analysis, and modeling, with emphasis on the use of computers. Section I involves data collection using a personal microcomputer system. One paper presents a tutorial on using a PC-based motor control composed of an electronic circuit to adjust the motion of a light microscope stage through a software program. Other papers discuss computer methods in nuclei cartography and a computer-assisted quantitative receptor autoradiography in studying receptor density distribution. Section II deals with data analysis and some computer programs for kinetic modeling of gene expression in neurons. The book also discusses a computerized analysis of opioid receptor heterogeneity by ligand binding in test animals using computerized programs instead of employing manual or graphical methods. Computerized curve-fitting allows the researcher to utilize a more precise mathematical model to describe the binding of one ligand to one class of sites. Section III evaluates data modeling and simulations and describes the practicality of using computers to design model ion channels. Another paper discusses a graphical interaction program called MEMPOT to simulate an electrophysiological investigation of the properties of the membrane potential in stimulated cells. The book also presents a quantitative data gathered from computer simulation of the factors that affect neuronal density per measured sections. The book is suitable for microbiologists, biochemists, neuroscientists, and researchers in the field of medical research, as well as for advanced computer programmers in medical research work.

Autoren/Hrsg.

Conn, P. Michael

Leseproben

Contributors to Volume 10

Peter Århem(17),     Nobel Institute for Neurophysiology, Karolinska Institute, S-104 01 Stockholm, Sweden

U. Arvidsson(7),     Department of Anatomy, Karolinska Institute, S-104 01 Stockholm, Sweden

Peter H. Barry(29),     School of Physiology and Pharmacology, University of New South Wales, Sidney, New South Wales 2033, Australia

Pascale Boulenguez(8),     Laboratoire de Neurobiologie, Centre National de la Recherche Scientifique, 13402 Marseille, France

Michael Brunner(3),     Fachbereich Biologie, Universität Kaiserslautern, D-675 Kaiserslautern, Germany

Kevin Bush(30),     Department of Molecular Biology, School of Osteopathic Medicine, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey 08084

James P. Butler(16),     Department of Environmental Science and Physiology, Harvard School of Public Health, Boston, Massachusetts 02115

K. Carlsson(7),     Department of Physics, The Royal School of Technology, S-100 44 Stockholm, Sweden

L. Charron(23),     Departments of Medicine and Physiology, University of Montreal, Montreal, Quebec H2W 1T8, Canada

Brenda J. Claiborne(19),     Division of Life Sciences, University of Texas at San Antonio, San Antonio, Texas 78249

J.H. Cocatre-Zilgien(14, 15),     Department of Entomology, University of Illinois, Urbana, Illinois 61801

G. Colliot(5),     INSERM, U314, Hôpital Maison Blanche, 51092 Reims, France

R. John Cork(25),     Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907

G. Corkidi(5),     Centro de Instrumentos, Universidad Nacional Autonoma de Mexico, Cd. Universitaria, C. P. 045510, Mexico D.F., Mexico

Frans Cornelissen(18),     Department of Physiology, Janssen Research Foundation, B-2340 Beerse, Belgium

C. Costa(32),     Department of Neurology, Santa Maria Hospital, 1600 Lisbon, Portugal

P. Delaère(32),     Laboratoire de Neuropathologie Escourolle, Hôpital de la Salpêtrière, 75651 Paris, France

F. Delcomyn(14, 15),     Department of Entomology, University of Illinois, Urbana, Illinois 61801

Victor H. Denenberg(9, 10),     Biobehavioral Sciences Graduate Degree Program, University of Connecticut, Storrs, Connecticut 06269

C. Duyckaerts(32),     Laboratoire de Neuropathologie Escourolle, Hôpital de la Salpêtrière, 75651 Paris, France

Sverker Eneström(6),     Department of Pathology, Linköping University, S-581 85 Linköping, Sweden

William S. Evans(16),     Department of Medicine, University of Virginia Health Sciences Center, National Science Foundation, Center for Biological Timing, Charlottesville, Virginia 22908

M. Freire(20),     Instituto Cajal, E-28002 Madrid, Spain

Hugo Geerts(18),     Department of Physiology, Janssen Research Foundation, B-2340 Beerse, Belgium

George L. Gerstein(4),     Department of Neuroscience, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104

James L. Hargrove(11),     Department of Foods and Nutrition, University of Georgia, Athens, Georgia 30602

Diane K. Hartle(11),     Department of Pharmacology and Toxicology, College of Pharmacy, University of Georgia, Athens, Georgia 30602

J.-J. Hauw(32),     Laboratoire de Neuropathologie Escourolle, Hôpital de la Salpêtrière, 75651 Paris, France

E.C. Hirsch(5),     Laboratoire de Médecine Expérimentale, INSERM, Hôpital de la Salpêtrière, 75651 Paris, France

William R. Holmes(31),     Department of Biological Sciences, Ohio University, Athens, Ohio 45701

Christian Hoock(3),     Fachbereich Biologie, Universität Kaiserslautern, D-675 Kaiserslautern, Germany

Dale Huff(30),     Department of Pathology, Magee Women’s Hospital, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213

Claire E. Hulsebosch(21),     Department of Anatomy and Neurosciences, Marine Biomedical Institute, University of Texas Medical Branch, Galveston, Texas 77555

Martin G. Hulsey(11),     Department of Foods and Nutrition, University of Georgia, Athens, Georgia 30602

Staffan Johansson(17),     Nobel Institute for Neurophysiology, Karolinska Institute, S-104 01 Stockholm, Sweden

Michael L. Johnson(16),     Department of Pharmacology, University of Virginia Health Sciences Center, National Science Foundation, Center for Biological Timing, Charlottesville, Virginia 22908

Stephen W. Jones(28),     Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio 44106

Gerry H. Kenner(9, 10),     Thermoluminescence Laboratory, Division of Radiobiology, University of Utah, Salt Lake City, Utah 84112

Uwe T. Koch(3),     Fachbereich Biologie, Universität Kaiserslautern, D-675 Kaiserslautern, Germany

Dimitri M. Kullmann(22),     Department of Pharmacology, School of Medicine, University of California, San Francisco, San Francisco, California 94143

Hsin-yi Lee(30),     Department of Biology, Rutgers University, Camden, New Jersey 08102

O. Lejeune(5),     INSERM, U289, Hôpital de la Salpêtrière, 75651 Paris, France

Erich Lieth(24),     Department of Neurobiology, Harvard Medical School, Cambridge, Massachusetts 02138

J.P. Messier(23),     Departments of Medicine and Physiology, University of Montreal, Montreal, Quebec H2W 1T8, Canada

K. Mossberg(7),     Department of Physics, The Royal School of Technology, S-100 44 Stockholm, Sweden

Peter J. Munson(12),     Analytical Biostatistics Section, Division of Computer Research and Technology, National Institutes of Health, Bethesda, Maryland 20892

Robert G....