Disease-modifying Therapy in Vasculitides

Softcover Nachdruck of the original 1. Auflage 2001
ISBN: 978-3-0348-9485-2
Verlag: Birkhäuser Basel

Buch, Englisch, 206 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 341 g

Reihe: Progress in Inflammation Research

Especially the past two decades have seen renewed interest in the

vasculitides. In this volume an international expert group presents the

current state of knowledge and concentrates on principles of immune

modulating therapy. Drawing from their work in rheumatology, nephrology,

internal medicine, connective tissue disease and clinical immunology,

they present new concepts in classificiation, diagnosis and

pathophysiology of the vasculitides. Evidence from experimental and

clinical trials is reviewed, as well as the outlook for further

research.

Zielgruppe

Research

Autoren/Hrsg.

Cohen Tervaert, Jan W.

Kallenberg, Cees G.M.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie

Inhaltsverzeichnis

Systemic vasculitides, an introduction.- Standard therapeutic regimens for vasculitis.- Tumor necrosis factor (TNF) inhibition in the treatment of vasculitis.- Methotrexate as an alternative to classic immunosuppressive therapies.- Intravenous immunoglobulin as immuno-modifying treatment.- T-cell directed treatment: anti-thymocyte globulin.- New immunosuppressants: mycophenolate mofetil and 15-deoxyspergualin.- Interferon-? for the treatment of virus-related systemic vasculitides.- Autologous stem cell therapy for systemic vasculitis.- Prevention of relapsing disease in anti-neutrophil cytoplasmic antibody related necrotizing small-vessel vasculitis: the role for autoantibody guided and anti-bacterial treatment.