Target Organ Toxicity

Volume 1
1. Auflage 2020
ISBN: 978-0-367-25645-6
Verlag: Taylor & Francis

Buch, Englisch, 230 Seiten, Format (B × H): 178 mm x 254 mm, Gewicht: 453 g

Reihe: Routledge Revivals

First published in 1986: The purpose of these volumes is to provide a valuable reference for established investigators and postgraduate students in toxicology.

Autoren/Hrsg.

Cohen, Gerald M.

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

1. Basic Principles of Target Organ Toxicity 2. Role of Pharmacokinetics in Rationalizing Tissue Distribution 3. The Role of Metabolic Activation in Target Organ Toxicity 4. Role of Excretion 5. Species Variation in Target Organ Toxicity 6. The Importance of Tissue-Specific Biochemistry in the Determination of Target Organ Toxicity 7. Role of Key Defense Systems in Target Organ Toxicity 8. The Liver as a Target Organ for Toxicity 9. The Nervous System as a Target Organ for Toxicity

Über Autor(innen)

Gerald M. Cohen Ph.D. is Head of the Toxicology Unit, Department of Pharmacology, The School of Pharmacy, University of London.