Pharmaceutical Applications of Dendrimers

Erscheinungsjahr 2019
ISBN: 978-0-12-814527-2
Verlag: Elsevier Science Publishing Co Inc

Buch, Englisch, 398 Seiten, Format (B × H): 191 mm x 235 mm, Gewicht: 750 g

Reihe: Micro & Nano Technologies

Pharmaceutical Applications of Dendrimers explores the applications of dendrimers in the solubilization of hydrophobic active ingredients, drug delivery, gene delivery, imaging, diagnosis and photodynamic therapy. The book discusses the diagnostic applications of dendrimers, including their use as MRI contrast agents and in the imaging of diseased areas. In addition, the anti-inflammatory, antimicrobial and antiviral properties of PPI and PAMAM are also covered, along with a discussion on photosensitizers, such as rose Bengal and protoporphyrin IX that have been delivered using PAMAM and PPI dendrimers for the treatment of cancer.

This book is an important research reference for those who want to learn more about the development of dendrimer-based solutions for drug delivery.

Zielgruppe

<p>Materials scientists and biomedical researchers who are looking to learn more about how dendrimers can be used to create more efficient drug delivery solutions</p>

Autoren/Hrsg.

Chauhan, Abhay Singh

Kulhari, Hitesh

Fachgebiete

• Technische Wissenschaften Maschinenbau | Werkstoffkunde Technische Mechanik | Werkstoffkunde Materialwissenschaft: Biomaterialien, Nanomaterialien, Kohlenstoff
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Pharmazeutische Technologie

Inhaltsverzeichnis

1. Dendrimers: Introduction, types and properties
2. Dendrimers as solubility enhancer or excipient
3. Dendrimers as therapeutic agent/drug
4. Biocompatibility and toxicity of dendrimers
5. Dendrimers as drug delivery carrier
6. Dendrimers for the delivery of biological drugs
7. Pharmacokinetic considerations in design of dendrimer-based nanomedicines
8. Design of dendrimer-based prodrugs
9. Stimuli-responsive dendrimers in drug delivery
10. Dendrimer-based targeted drug delivery
11. Dendrimers in photodynamic therapy
12. Diagnostic applications of dendrimer based nanovectors
13. Overview of current clinical status of dendrimer-based formulations

Über Autor(innen)

Chauhan, Abhay Singh
Abhay Singh Chauhan is Associate Professor, School of Pharmacy at the Medical College of Wisconsin, USA. He was previously Director of Pharmaceutical Nanotechnology at Concordia University, USA. His research is in the area of nanopharmaceuticals.

Kulhari, Hitesh
Dr. Hitesh Kulhari is an Assistant Professor at the School of Nano Sciences, Central University of Gujarat, India. He completed his PhD at RMIT University, Australia, from 2011 to 2015. Prior to that, he earned his Master of Pharmacy at the Bundelkhand University, India, in 2008.

Dr. Kulhari's remarkable contributions have been recognized with prestigious awards, including the Prof CNR Rao Research Excellence Award in Material Science, the INSPIRE Faculty Award, and the Early Career Research Award. His research interests include nanomedicines and nanobiomaterials.