E-Book, Englisch, Band 7, 460 Seiten
Reihe: Protein Reviews
Calderwood / Jörnvall Cell Stress Proteins
1. Auflage 2009
ISBN: 978-0-387-39717-7
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark
E-Book, Englisch, Band 7, 460 Seiten
Reihe: Protein Reviews
ISBN: 978-0-387-39717-7
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark
This book surveys the current knowledge concerning the expression and function of stress proteins in different organisms, ranging from prokaryotes to humans. It provides an overview of the diversity and complex evolutionary history of cell stress proteins and describes their function and expression in different eukaryote models. The book will appeal to researchers and scientists in biochemistry, cell biology, microbiology, immunology, and genetics.
Autoren/Hrsg.
Weitere Infos & Material
1;Cell Stress Proteins;3
2;Contents;6
3;Foreword;9
4;Acknowledgement;10
5;List of Contributors;11
6;Introduction: Heat Shock Proteins— From Drosophila Stress Proteins to Mediators of Human Disease;14
7;Stress Response and Molecular Chaperones;18
7.1;Biology of the Heat Shock Response and Stress Conditioning;19
7.2;Bacterial Stress Sensors;48
7.3;Unfolded Protein Response: Contributions to Development and Disease;69
8;Molecular Mechanisms of Stress Protein Expression;101
8.1;Genetic Models of HSF Function;102
8.2;HSF1 and HSP Gene Regulation;133
9;Cellular Stress Proteins;151
9.1;Small Heat Shock Proteins in Physiological and Stress- Related Processes;152
9.2;Large Mammalian hsp70 Family Proteins, hsp110 and grp170, and Their Roles in Biology and Cancer Therapy;187
10;Molecular Chaperones and Protein Folding;215
10.1;Regulation of Hsp70 Function: Hsp40 Co- Chaperones and Nucleotide Exchange Factors;216
10.2;Protein Disassembly by Hsp40–Hsp70;235
10.3;Mammalian HSP40/DnaJ Chaperone Proteins in Cytosol;262
11;Role of Molecular Chaperones in Cell Regulation;285
11.1;FKBP Co-Chaperones in Steroid Receptor Complexes;286
11.2;Up and Down;318
11.3;Role of Cdc37 in Protein Kinase Folding;331
12;Intracellular and Extracellular Stress Proteins in Human Disease;343
12.1;Targeting Hsp90 in Cancer and Neurodegenerative Disease;344
12.2;gp96 and Tumor Immunity;367
12.3;Immunoregulatory Activities of Extracellular Stress Proteins;380
12.4;Heat Shock Proteins and Neurodegenerative Diseases;399
12.5;Heat Shock Proteins in the Progression of Cancer;425
13;Index;454
14;Color Plate I;463
15;Color Plate II;464
