Brown / Gregory / Twelves A Practical Guide to Designing Phase II Trials in Oncology

1. Auflage 2014
ISBN: 978-1-118-76362-9
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 256 Seiten, E-Book

Reihe: Statistics in Practice

How to identify optimal phase II trial designs
Providing a practical guide containing the information needed tomake crucial decisions regarding phase II trial designs, APractical Guide to Designing Phase II Trials in Oncology setsforth specific points for consideration between the statisticianand clinician when designing a phase II trial, including issuessuch as how the treatment works, choice of outcome measure andrandomization, and considering both academic and industryperspectives. A comprehensive and systematic library of availablephase II trial designs is included, saving time otherwise spentconsidering multiple manuscripts, and real-life practical examplesof using this approach to design phase II trials in cancer aregiven.
A Practical Guide to Designing Phase II Trials in Oncology:
* Offers a structured and practical approach to phase II trialdesign.
* Considers trial design from both an academic and industryperspective.
* Includes a structured library of available phase II trialdesigns.
* Is relevant to both clinical and statistical researchers at alllevels
* Includes real life examples of applying this approach.
* For those new to trial design, A Practical Guide toDesigning Phase II Trials in Oncology will be a uniqueand practical learning tool, providing an introduction to theconcepts behind informed decision making in phase II trials. Formore experienced practitioners, the book will offer an overview ofnew, less familiar approaches to phase II trial design, providingalternative options to those which they may have previouslyused.

Autoren/Hrsg.

Brown, Sarah R.

Gregory, Walter M.

Twelves, Christopher J.

Brown, Julia M.