Buch, Englisch, 140 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 248 g
Reihe: Springer Theses
Underlying Physics and Developments for Breast Imaging
Buch, Englisch, 140 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 248 g
Reihe: Springer Theses
ISBN: 978-3-030-60435-6
Verlag: Springer International Publishing
X-ray imaging is a corner stone of breast cancer diagnosis. By exploiting the phase shift of X-rays rather than their attenuation, phase-contrast tomography has the potential to dramatically increase the visibility of small and low contrast features, thus leading to better diagnosis. This thesis presents research on the first synchrotron-based project developing a clinical phase-contrast breast computed tomography (CT) setup at Elettra, the Italian Syncrotron Radiation Facility. This book includes a comprehensive theoretical background on propagation-based phase-contrast imaging, exploring and extending the most recent image formation models. Along with theory, many practical implementation and optimization issues, ranging from detector-specific processing to setup geometry, are tackled on the basis of a large number of experimental evidences. Most of the modelling results and data analysis have general validity, being a valuable framework for optimization of phase-contrast setups. Results obtained at synchrotron are also compared with "real world" laboratory sources: both a first-of-its-kind comparison with one of the few hospital breast CT systems and a state-of-the-art implementation of monochromatic phase-contrast micro-tomography with a conventional rotating anode source are presented. On a more general level, this work sheds a light on the importance of synchrotron-based clinical programs, which are key to trigger the long-anticipated transition of phase-contrast imaging from synchrotrons to hospitals.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Naturwissenschaften Physik Angewandte Physik Biophysik
- Naturwissenschaften Biowissenschaften Angewandte Biologie Biophysik
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Bildgebende Verfahren, Nuklearmedizin, Strahlentherapie Radiologie, Bildgebende Verfahren
- Naturwissenschaften Physik Quantenphysik Atom- und Molekülphysik
Weitere Infos & Material
Introduction.- Physics of Propagation-based X-ray Tomography.- Propagation-based Breast CT and SYRMA-3D Project.- Detector and Pre-processing.- Experimental Optimization of Propagation-based BCT.- Three-Dimensional Imaging: A Clinically Oriented Focus.- Do We Need Clinical Applications in Synchrotrons?.- Conclusions.
