Bräse / Banert Organic Azides

Syntheses and Applications
1. Auflage 2011
ISBN: 978-0-470-68252-4
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 536 Seiten, E-Book

* Most current state-of-the-art overview of this important classof compounds, encompassing many new and emergingapplications
* The number of articles on organic azides continues to increasetremendously; on average, there are more than 1000 new publicationsa year
* Covers basic chemistry as well as state-of-the-art applicationsin life science and materials science
* World-ranked authors describe their own research in the widercontext of azide chemistry
* Includes a chapter on safe synthesis and handling (azides candecompose explosively)

Autoren/Hrsg.

Bräse, Stefan

Banert, Klaus

Inhaltsverzeichnis

Forewords: Rolf Huisgen, Valery Fokin, and Barry Sharpless.
Preface.
List of Contributors.
Abbreviations.
PART 1: SYNTHESIS AND SAFETY.
1 Lab-Scale Synthesis of Azido Compounds: Safety Measures andAnalysis (Thomas Keicher and Stefan Löbbecke).
2 Large-Scale Preparation and Usage of Azides (JürgenHaase).
3 Synthesis of Azides (Teresa M.V.D. Pinho e Melo).
4 Azides by Olefin Hydroazidation Reactions (JérômeWaser and Erick M. Carreira).
PART 2: REACTIONS.
5 The Chemistry of Vinyl, Allenyl, and Ethynyl Azides (KlausBanert).
6 Small Rings by Azide Chemistry (Thomas L. Gilchrist and MariaJosé Alves).
7 Schmidt Rearrangement Reactions with Alkyl Azides (ScottGrecian and Jeffrey Aubé).
8 Radical Chemistry with Azides (Ciril Jimeno and PhilippeRenaud).
9 Cycloaddition Reactions with Azides: An Overview (ChristineSchilling, Nicole Jung and Stefan Bräse).
10 Dipolar Cycloaddition Reactions in Peptide Chemistry(Christian Wenzel Tornøe and Morten Meldal).
11 Photochemistry of Azides: The Azide/Nitrene Interface (NinaGritsan and Matthew Platz).
12 Organoazides and Transition Metals (Werner R. Thiel).
PART 3: MATERIAL SCIENCES.
13 Azide-containing High Energy Materials (Thomas M.Klapötke and Burkhard Krumm).
14 Azide Chemistry in Rotaxane and Catenane Synthesis(Stéphanie Durot, Julien Frey, Jean-Pierre Sauvage andChristian Tock).
PART 4: APPLICATION IN BIOORGANIC CHEMISTRY.
15 Aza-Wittig Reaction in Natural Product Syntheses (FranciscoPalacios, Concepción Alonso, Domitila Aparicio, GloriaRubiales and Jesús M. de los Santos).
16 Azides in Carbohydrate Chemistry (Henning S.G. Beckmann andValentin Wittmann).
Index.

Über Autor(innen)

Stefan Bräse was born in Kiel, Germany, in 1967 andstudied chemistry in Göttingen, Bangor (UK) and Marseille(France). In 1995, he obtained his doctorate after working withArmin de Meijere at the University of Göttingen. Afterpost-doctoral appointments at Uppsala University, Sweden (J.-E.Bäckvall) and The Scripps Research Institute, La Jolla, USA(K. C. Nicolaou), he began his independent research career at theRWTH Aachen associated with Dieter Enders in1997 and finished hishabilitation in 2001. He became Professor at the University of Bonnthat same year. Since 2003, he is Full Professor at the Universityof Karlsruhe - in October 2009 renamed to the KarlsruheInstitute of Technology. Stefan Bräse has published more than100 publications and is recipient of the ORCHEM award in 2000. Hisresearch interests include methods in drug-discovery (includingdrug delivery), combinatorial chemistry towards the synthesis ofbiologically active compounds, total synthesis of natural productsand nanotechnology.