Buch, Englisch, 290 Seiten, Gewicht: 1202 g
Buch, Englisch, 290 Seiten, Gewicht: 1202 g
ISBN: 978-1-55581-240-9
Verlag: Taylor & Francis
Designed to assist clinicians in the diagnosis and therapy of patients with suspected viral encephalitis. • Presents information according to the clinical and epidemiological information available at the time of presentation of the patients rather than according to principles of viral taxonomy. • Emphasizes neuropathological descriptions and pathogenesis concepts, reflecting the authors’ belief that an understanding of pathogenesis facilitates the diagnostic process and is central to therapeutic intervention. • Covers the full range of human encephalitis/encephalopathy, including HIV/AIDS, prion diseases, and smallpox.
This title is published by the American Society for Microbiology Press and distributed by Taylor and Francis in rest of world territories.
Autoren/Hrsg.
Weitere Infos & Material
Table of Contents
Preface
Acknowledgements
Section I. Introduction
1. Pathological Features of Encephalitis in Humans
Sources of Information on the Pathology of Encephalitis
Naked-Eye Examination of the Brain and Routine Light Microscopy
Immunocytochemistry, PCR, and In Situ Hybridization
Electron Microscopy
Pathological Features Common to Most Forms of Viral Encephalitis
Pathological Features Restricted to Certain Forms of Encephalitis
Mode of Entry of Viruses into the Nervous System
Selective Vulnerability of Cells of the Central Nervous System
Tempo of the Disease Process
Role of the Immune Response
Complications and Sequelae
The Need for Autopsies
2. Diagnostic Evaluation
Differentiation of Encephalitis from Other Conditions
Types of Encephalitis: Key Initial Questions
Clinical Classification of Encephalitis
Diagnostic Evaluation of Encephalitis
Diagnostic Virology and Serology
Encephalitis of Undetermined Etiology
3. Management Decisions in Acute Encephalitis
Common Management Issues
Antiviral and Immunomodulating Therapies
Therapy by Type of Encephalitis
Clinical Evaluation for Acute Management
Acute Management Decisions
Reduction of Raised Intracranial Pressure
Control of Seizures
Management in the Recovery Period
Appendix: Encephalitis Treatment Checklist Arranged by Clinical Classification
Section II. Acute Sporadic Encephalitis
4. Herpes Simplex Encephalitis
Introduction and Classification
HSV
Historical Considerations
Pathology of HSE
Pathology of Atypical HSV-1 Encephalitis and HSV-2 Encephalitis and Myelitis
Pathogenesis of HSE
Clinical Evaluation of HSE
Therapy, Course, and Outcomes
Recurrent Encephalitis
Neonatal Nerpes Simplex Infection
5. Systemic Viral Diseases and Encephalitis
Exanthematous Diseases
Mumps
Epstein-Barr Virus--Infectious Mononucleosis--Glandular Fever
Adenovirus
Gastroenteritis-Rotaviruses
Hepatitis Viruses
6. Encephalitis Viruses Transmitted from Animals
Sporadic Arbovirus Infections
Lymphocytic Choriomeningitis Virus
Rabies
Herpes B Virus of Monkey--Herpesvirus simiae--Cercopithecine Herpesvirus
Section III. Acute Parainfectious Immune-Mediated Encephalomyelitis
7. Pathology of Allergic Forms of Encephalomyelitis
Pathology of Human Perivenous Encephalitis
Pathology of Acute Hemorrhagic Leukoencephalitis
Acute Parainfectious Encephalopathy
Pathogenesis of Allergic Encephalitis
8. Clinical Syndromes Including Smallpox and Measles
ADEM
Acute Cerebellar Ataxia and Related Syndromes
Brain Stem ADEM, Including Bickenstaff's Brain Stem Encephalitis
Miller Fisher Syndrome
Acute Transverse Myelitis
Acute Hemorrhagic Leukoencephalopathy (Hurst)
Acute Encephalopathy, Including Reye's Syndrome
Postviral Stroke
Smallpox and Its Vaccination
Measles
9. Varicella-Zoster Virus: the Paradox of Immune Mediation and Immunocompromise
Chicken Pox
Zoster
Section IV. Acute Epidemic Encephalitis
10. Influenza Virus, Enteroviruses, and Other Epidemic Viruses
Human-to-Human Transmission
Animal-to-Human Transmission: Nipah Virus
Unknown Means of Transmission
11. The Arboviruses
Pathology
Pathogenesis
Diagnosis and Management
Mosquito-Borne Encephalitides
Tick-Borne Encephalitides
Section V. Subacute and Chronic Encephalitis and Prion Diseases
12. HIV/AIDS
The Pathogenesis and Pathology of AIDS
Systemic Pathology of AIDS
Neuropathology of HIV Infection
Pre-AIDS Neuropathology in Untreated Individuals: Lymphocytic Meningitis
AIDS Neuropathology
Neuronal Pathology and Its Pathogenesis
Vascular Pathology
AIDS-Associated Myelopathy and HIV Myelitis
Influence of Antiretroviral Treatment on the Neuropathology of AIDS
Clinical Features of Early HIV Disease in the CNS
Antiretroviral Therapy
Clinical Features of AIDS in the CNS
Pediatric AIDS
13. Encephalitis in Immunocompromised Patients
PML
CMV Encephalitis and Radiculomyelitis
Enteroviral CNS Infections in Primary Hypogammaglobulinemia or Agammaglobulinemia
IME
Encephalitis Associated with Organ Transplantation and Bone Marrow Allografting
14. Encephalitis in Immunocompetent Patients
SSPE
PRP
HAM/TSP
Rasmussen's Encephalitis
Vilyuisk Encephalitis--Bokhoror
Borna Disease
15. Creutzfeldt-Jakob Disease and Other Prion Disorders
Pathology
Pathogenesis of CJD
Diagnosis and Management
Infection Control
Index
