Nucleic Acids

Structures, Properties and Functions
2000
ISBN: 978-0-935702-49-1
Verlag: MIT Press

Buch, Englisch, 794 Seiten, Book, Format (B × H): 180 mm x 255 mm, Gewicht: 1583 g

This is a comprehensive and up-to-date account of the structures and physical chemistry properties of nucleic acids, with special emphasis on biological function. The book has been carefully organised to meet the needs of molecular biologists, physical biochemists and physical chemists with only a basic understanding of physical chemistry and molecular biology. Nucleic Acids will serve as a textbook in physical biochemistry and biophysical chemistry classes, as well as a supplemental text in courses on nucleic acid biochemistry or molecular biology, and as a personal reference for students and researchers in these fields.

Zielgruppe

Lower undergraduate

Autoren/Hrsg.

Bloomfield, Victor A

Crothers, Donald M

Tinoco Jr, Ignacio

Tinoco, Ignacio

Inhaltsverzeichnis

Introduction.- Bases, Nucleosides and Nucleotides.- Chemical and Enzymatic Methods.- Nucleic Acid Structures from Diffraction Methods.- Structure and Dynamics by NMR.- Electronic and Vibrational Spectroscopy.- Theoretical Methods.- Conformational Changes.- Size and Shape of Nucleic Acids in Solution.- Supercoiled DNA.- Interaction of Nucleic Acids with Water and Ions.- Interaction and Reaction with Drugs.- Protein-Nucleic Acid Interactions.- Higher Order Structure.- Index.

Über Autor(innen)

VICTOR A. BLOOMFIELD, University of MinnesotaDONALD M. CROTHERS, Yale UniversityIGNACIO TINOCO, University of California, Berkeley